The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Abstract Background Long non-coding RNAs (lncRNAs) are important epigenetic regulators,
which play critical roles in diverse physiological and pathological processes. However, the …

The long non-coding RNAs associating with other molecules can coordinate several
physiological processes and their dysfunction can impact diverse human diseases. To date …

Abstract Argonaute 2 (AGO2), the core component of microRNA (miRNA)-induced silencing
complex, plays a compelling role in tumorigenesis and aggressiveness. However, the …

Rationale: circular RNAs (circRNAs) have been demonstrated to play a crucial role in cancer
progression. KIAA1429, a key component of the m6A methyltransferase complex, has …

Gemcitabine (GEM) resistance is a major challenge for chemotherapy of pancreatic cancer.
Previous studies have reported on the role of long noncoding RNA (lncRNA) in …

Background RNA regulation is significantly dependent on its binding protein partner, known
as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs …

The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …

Aims Cardiotoxicity leading to heart failure (HF) is a growing problem in many cancer
survivors. As specific treatment strategies are not available, RNA discovery pipelines were …