Treatment of drug-induced liver injury

R Teschke - Biomedicines, 2022 - mdpi.com
Current pharmacotherapy options of drug-induced liver injury (DILI) remain under
discussion and are now evaluated in this analysis. Needless to say, the use of the offending …

Advances in Idiosyncratic Drug-Induced Liver Injury Issues: New Clinical and Mechanistic Analysis Due to Roussel Uclaf Causality Assessment Method Use

R Teschke, G Danan - International Journal of Molecular Sciences, 2023 - mdpi.com
Clinical and mechanistic considerations in idiosyncratic drug-induced liver injury (iDILI)
remain challenging topics when they are derived from mere case narratives or iDILI cases …

Human Leucocyte Antigen Genetics in Idiosyncratic Drug-Induced Liver Injury with Evidence Based on the Roussel Uclaf Causality Assessment Method

R Teschke, G Danan - Medicines, 2024 - mdpi.com
The human leucocyte antigen (HLA) allele variability was studied in cohorts of patients with
idiosyncratic drug-induced liver injury (iDILI). Some reports showed an association between …

Idiosyncratic DILI and RUCAM under one hat: The global view

R Teschke, G Danan - Livers, 2023 - mdpi.com
Drugs are prescribed worldwide to treat diseases but with the risk of idiosyncratic drug-
induced liver injury (iDILI). The most important difficulty is how best to establish causality …

Idiosyncratic DILI: Immunology in Cases with Evidence Based on RUCAM

R Teschke - Journal of Modern Medicinal Chemistry, 2023 - synergypublishers.com
Idiosyncratic drug induced liver injury (iDILI) is a multifaceted and fairly well described liver
disease, but there is yet some uncertainty on the role of immune systems triggering the liver …