Privileged structures have been widely used as an effective template in medicinal chemistry
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …

Apoptosis is a primary characteristic in the pathogenesis of liver disease. Hepatic apoptosis
is regulated by autophagic activity. However, mechanisms mediating their interaction remain …

Despite the challenges posed by drug resistance and side effects, chemotherapy remains a
pivotal strategy in cancer treatment. A key issue in this context is macroautophagy …

Although cisplatin is one of the most common antineoplastic drug, its successful utilisation in
cancer treatment is limited by the drug resistance. Multiple attempts have been made to find …

Background Cisplatin (CP) or cis-diammine dichloroplatinum (II) is a platinum based
standard antineoplastic drug which is used against variety of solid tumors and neoplasms …

Abstract Cabergoline (CAB), the first-line drug for treatment of prolactinomas, is effective in
suppressing prolactin hypersecretion, reducing tumor size, and restoring gonadal function …

Background Metformin, a first-line antidiabetic drug, has recently been reported with
anticancer activities in various cancers; however, the underlying mechanisms remain …

Metformin, a first‐line antidiabetic drug, has been reported with anticancer activities in many
types of cancer. However, its molecular mechanisms remain largely unknown. As a member …

Introduction The incidence and mortality rates of lung cancer rank top in the different types of
cancers in China. Licochalcone A (LA) is a flavonoid extracted from the roots of licorice with …

Background Lung cancer is the leading cause of cancer-related death worldwide. In addition
to surgical resection, which is considered first-line treatment at early stages of the disease …