Towards a deeper understanding of the vaginal microbiota
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …
live in close association with the vaginal epithelium and rely on host tissues for resources …
The microbiome and gynaecological cancer development, prevention and therapy
P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …
microbiome, which has an essential role in maintaining health and homeostasis. In the …
Roles of the microbiota of the female reproductive tract in gynecological and reproductive health
B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …
Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
[HTML][HTML] Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix
P Łaniewski, MM Herbst-Kralovetz - npj Biofilms and Microbiomes, 2021 - nature.com
Bacterial vaginosis (BV) is an enigmatic polymicrobial condition characterized by a
depletion of health-associated Lactobacillus and an overgrowth of anaerobes. Importantly …
depletion of health-associated Lactobacillus and an overgrowth of anaerobes. Importantly …
[HTML][HTML] The cervicovaginal mucus barrier
G Lacroix, V Gouyer, F Gottrand… - International Journal of …, 2020 - mdpi.com
Preterm births are a global health priority that affects 15 million babies every year worldwide.
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …
Influence of Biofilm Formation by Gardnerella vaginalis and Other Anaerobes on Bacterial Vaginosis
Bacterial vaginosis (BV) is the worldwide leading vaginal disorder among women of
reproductive age. BV is characterized by the replacement of beneficial lactobacilli and the …
reproductive age. BV is characterized by the replacement of beneficial lactobacilli and the …
[HTML][HTML] The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
E Jašarević, EM Hill, PJ Kane, L Rutt, T Gyles… - Nature …, 2021 - nature.com
Newborns are colonized by maternal microbiota that is essential for offspring health and
development. The composition of these pioneer communities exhibits individual differences …
development. The composition of these pioneer communities exhibits individual differences …
[HTML][HTML] Gardnerella vaginalis as a Cause of Bacterial Vaginosis: Appraisal of the Evidence From in vivo Models
S Morrill, NM Gilbert, AL Lewis - Frontiers in cellular and infection …, 2020 - frontiersin.org
Koch's postulates dictate the use of experimental models to illustrate features of human
disease and provide evidence for a singular organism as the cause. The underlying cause …
disease and provide evidence for a singular organism as the cause. The underlying cause …
The cervicovaginal microbiota-host interaction modulates Chlamydia trachomatis infection
The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …