Epithelial ovarian cancer and the immune system: biology, interactions, challenges and potential advances for immunotherapy

AM Macpherson, SC Barry, C Ricciardelli… - Journal of clinical …, 2020 - mdpi.com
Recent advances in the understanding of immune function and the interactions with tumour
cells have led to the development of various cancer immunotherapies and strategies for …

Tumor-infiltrating lymphocytes (TILs) in epithelial ovarian cancer: heterogeneity, prognostic impact, and relationship with immune checkpoints

D Hudry, S Le Guellec, S Meignan, S Becourt… - Cancers, 2022 - mdpi.com
Simple Summary Outcomes of ovarian cancer (OC) patients remain poor despite recent
advances in oncology. Immunotherapy has proven to be beneficial in treating selected …

Immune cell infiltration-based signature for prognosis and immunogenomic analysis in breast cancer

S Wang, Q Zhang, C Yu, Y Cao, Y Zuo… - Briefings in …, 2021 - academic.oup.com
Breast cancer is one of the most human malignant diseases and the leading cause of cancer-
related death in the world. However, the prognostic and therapeutic benefits of breast cancer …

A random forest-based metabolic risk model to assess the prognosis and metabolism-related drug targets in ovarian cancer

H Zhang, M Chi, D Su, Y Xiong, H Wei, Y Yu… - Computers in Biology …, 2023 - Elsevier
As one of the most common gynecologic malignant tumors, ovarian cancer is usually
diagnosed at an advanced and incurable stage because of its early asymptomatic onset …

High-throughput and label-free enrichment of malignant tumor cells and clusters from pleural and peritoneal effusions using inertial microfluidics

Z Zhu, S Li, D Wu, H Ren, C Ni, C Wang, N Xiang, Z Ni - Lab on a Chip, 2022 - pubs.rsc.org
Accurate and rapid diagnosis of malignant pleural and peritoneal effusions is critical due to
potential association with advanced disease stages or progression. Traditional …

Development and validation of a novel 11-gene prognostic model for serous ovarian carcinomas based on lipid metabolism expression profile

M Zheng, H Mullikin, A Hester, B Czogalla… - International journal of …, 2020 - mdpi.com
(1) Background: Biomarkers might play a significant role in predicting the clinical outcomes
of patients with ovarian cancer. By analyzing lipid metabolism genes, future perspectives …

TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer

L Lu, W Ling, Z Ruan - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Extracellular vesicles (EVs) secreted from tumor-associated macrophages (TAMs) are
known to generate an immune-suppressive environment conducive to the development of …

Identification of disulfidptosis-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognosis model in colorectal cancer

Y Li, M Tang, W Dang, S Zhu, Y Wang - Journal of Cancer Research and …, 2023 - Springer
Background Colorectal cancer is the second leading cause of cancer-related deaths, which
imposes a significant societal burden. Regular screening and emerging molecular tumor …

HIF-1α is a rational target for future ovarian cancer therapies

X Wang, Z Du, T Xu, X Wang, W Li, J Gao, J Li… - Frontiers in …, 2021 - frontiersin.org
Ovarian cancer is the eighth most commonly diagnosed cancer among women worldwide.
Even with the development of novel drugs, nearly one-half of the patients with ovarian …

[HTML][HTML] The role of MEOX1 in non-neoplastic and neoplastic diseases

G Zeng, X Liu, X Su, Y Wang, B Liu, H Zhou… - Biomedicine & …, 2023 - Elsevier
Targeted gene therapy has shown durable efficacy in non-neoplastic and neoplastic
patients. Therefore, finding a suitable target has become a key area of research …