Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Abstract Type 2 diabetes (T2D) is a widely prevalent disease with substantial economic and
social impact for which multiple conventional and novel pharmacotherapies are currently …

Aging is a natural process, which plays a critical role in the pathogenesis of a variety of
diseases, ie, aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease …

Non-alcoholic fatty liver disease (NAFLD) comprises fatty liver (steatosis), non-alcoholic
steatohepatitis (NASH) and fibrosis/cirrhosis and may lead to end-stage liver failure or …

Patients with type 2 diabetes mellitus (T2DM) can have multiple comorbidities and
premature mortality due to atherosclerotic cardiovascular disease, hospitalization with heart …

Given the intersection between diabetes mellitus and cardiovascular disease (CVD),
pharmacologic agents used to treat type 2 diabetes mellitus must show cardiovascular …

Background Cardiovascular disease (CVD) is a leading cause of death globally. Recently,
dipeptidyl peptidase‐4 inhibitors (DPP4i), glucagon‐like peptide‐1 receptor agonists (GLP …

Diabetes mellitus increases the risk of developing heart failure, and the co-existence of both
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …

OBJECTIVE To determine whether metformin or lifestyle modification can lower rates of all-
cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes …

Metformin is the most widely used glucose lowering drug worldwide in the treatment of
patients with type 2 diabetes, since we have experience with this drug for more than 60 …