Neoplasms change over time through a process of cell-level evolution, driven by genetic
and epigenetic alterations. However, the ecology of the microenvironment of a neoplastic …

Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder. It is
characterized by two principal features, microcephaly present at birth and nonprogressive …

Androgen receptor (AR) gene aberrations are rare in prostate cancer before primary
hormone treatment but emerge with castration resistance. To determine AR gene status …

Understanding why some species have more genetic diversity than others is central to the
study of ecology and evolution, and carries potentially important implications for …

Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …

KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and
synonymous (Ks) substitution rates through model selection and model averaging. Since …

The field of molecular evolution has experienced explosive growth in recent years due to the
rapid accumulation of genetic sequence data, continuous improvements to computer …

Background Suaeda glauca (S. glauca) is a halophyte widely distributed in saline and sandy
beaches, with strong saline-alkali tolerance. It is also admired as a landscape plant with …

Mutation is the engine that drives evolution and adaptation forward in that it generates the
variation on which natural selection acts. Mutation is a random process that nevertheless …

Studies of evolution at the molecular level have experienced phenomenal growth in the last
few decades, due to rapid accumulation of genetic sequence data, improved computer …