Importance Use of prognostic gene expression profile (GEP) testing in cutaneous melanoma
(CM) is rising despite a lack of endorsement as standard of care. Objective To develop …

Cancer is one of the three leading causes of death worldwide. Even after successful therapy
and achieving remission, the risk of relapse often remains. In this context, dormant residual …

Despite significant progress in the development of treatment options, melanoma remains a
leading cause of death due to skin cancer. Advances in our understanding of the genetic …

Adjuvant systemic therapies are now routinely used following resection of stage III
melanoma, however accurate prognostic information is needed to better stratify patients. We …

Abstract Background Melanomas< 0.8 mm in Breslow depth have less than a 5% risk for
nodal positivity. Nonetheless, nodal positivity is prognostic for this group. Early identification …

Abstract Objective National Comprehensive Cancer Network (NCCN) guidelines for
cutaneous melanoma (CM) recommend physicians consider increased surveillance for …

Integrins are the major family of cell adhesion receptors in humans and essential for a wide
range of normal physiology, including formation and maintenance of tissue structure …

Simple Summary Myelofibrosis (MF) displays the worst prognosis among Philadelphia-
negative chronic myeloproliferative neoplasms. There is no curative therapy for MF, except …

Background A significant proportion of deaths from cutaneous melanoma occur among
patients with an initial diagnosis of stage 1 or 2 disease. The Decision-Dx Melanoma (DDM) …

Objective Although most patients diagnosed with early‐stage cutaneous melanoma (CM)
have excellent outcomes, because of the large number diagnosed each year, many will …