One‐Pot Multicomponent Reaction: A Highly Versatile Strategy for the Construction of Valuable Nitrogen‐Containing Heterocycles

S Nandi, R Jamatia, R Sarkar, FK Sarkar… - …, 2022 - Wiley Online Library
A large portion of the chemical subspace is the multi‐component reaction (MCR). Apart from
Domino reactions, MCR is one of the most promising routes for one‐pot synthesis. Thus …

Construction and Aromatization of Hantzsch 1, 4‐Dihydropyridines under Microwave Irradiation: A Green Approach

MM Heravi, V Zadsirjan - ChemistrySelect, 2022 - Wiley Online Library
Hantzsch reaction, leading to the synthesis of 1, 4‐dihydropyridines (1, 4‐DHPs) with
momentous biological activities and pharmacological properties is a well‐known MCR. In …

Synthesis and antioxidant activity of new lipophilic dihydropyridines

D da Costa Cabrera, E Santa-Helena, HP Leal… - Bioorganic …, 2019 - Elsevier
Abstract Dihydropyridines (DHPs) obtained from Hantzsch multicomponent reactions are an
important pharmaceutical class of compounds marketed as antihypertensive (eg, nifedipine …

Task-specific ionic liquid incorporating anionic heteropolyacid-catalyzed Hantzsch and Mannich multicomponent reactions. Ionic liquid effect probed by ESI-MS (/MS)

HGO Alvim, GA Bataglion, LM Ramos, AL de Oliveira… - Tetrahedron, 2014 - Elsevier
A task-specific ionic liquid with a Bronsted acid (1-(3-sulfopropyl)-3-methylimidazolium
hydrogen sulfate, namely MSI) bearing an anionic heteropolyacid derivative ([PW 12 O 40] …

5-Oxo-hexahydroquinoline: An attractive scaffold with diverse biological activities

S Ranjbar, N Edraki, O Firuzi, M Khoshneviszadeh… - Molecular Diversity, 2019 - Springer
Oxo-hexahydroquinoline (5-oxo-HHQ) represents a biologically attractive fused heterocyclic
core. Various synthetic analogs of 5-oxo-HHQ have been synthesized and assessed for …

p-Toluenesulfonic acid doped polystyrene (PS-PTSA): solvent-free microwave assisted cross-coupling-cyclization–oxidation to build one-pot diversely functionalized …

VV Shinde, SD Lee, YS Jeong, YT Jeong - Tetrahedron Letters, 2015 - Elsevier
A solvent-free environmentally benign approach for the synthesis of diversified pyrrole
derivatives has been described by the one-pot multicomponent reaction of aldehydes …

[HTML][HTML] EGFR, HER2 target based molecular docking analysis, in vitro screening of 2, 4, 5-trisubstituted imidazole derivatives as potential anti-oxidant and cytotoxic …

R Guda, G Kumar, R Korra, S Balaji, G Dayakar… - … of Photochemistry and …, 2017 - Elsevier
In our endeavor towards the development of potent molecules for cancer diseases, we have
designed and synthesized a series of 2, 4, 5-trisubstituted imidazole derivatives (B1–B24) …

One-Pot Green Synthesis and Biological Evaluation of Dimedone-Coupled 2, 3-Dihydrofuran Derivatives to Divulge Their Inhibition Potential against Staphylococcal …

M Shukla, G Mali, S Sharma, S Maji, VK Yadav… - ACS …, 2024 - ACS Publications
New therapeutic leads are in global demand against multiple drug-resistant Staphylococcus
aureus, as presently there is no drug of choice left to treat this pathogen. In the present work …

Antioxidant Properties of Phenolic Compounds in Renewable Parts of Crataegus pinnatifida inferred from Seasonal Variations

M Luo, X Yang, JY Hu, J Jiao, FS Mu… - Journal of food …, 2016 - Wiley Online Library
In this study, the effect of seasonal variations on Crataegus pinnatifida, changes in
antioxidant activity and active components in C. pinnatifida leaves, roots, twigs, and fruits …

Magnetically separable recyclable nano-ferrite catalyst for the synthesis of acridinediones and their derivatives under solvent-free conditions

P Mahesh, K Guruswamy, BS Diwakar… - Chemistry …, 2015 - academic.oup.com
Catalytic activity of nano-ferrite is explored in the synthesis of acridinedione and their
derivatives under benign conditions; a greener protocol is reported in terms of excellent …