A fresh start for IVM: capacitating the oocyte for development using pre-IVM
RB Gilchrist, TM Ho, M De Vos… - Human …, 2024 - academic.oup.com
BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …
clinical practice globally. However, recently there have been some seminal advances in our …
The Simulated Physiological Oocyte Maturation (SPOM) system in domestic animals: A systematic review
GR Leal, CAS Monteiro, L de Rezende Carvalheira… - Theriogenology, 2022 - Elsevier
Abstract Simulated Physiological Oocyte Maturation (SPOM) mimics in vitro the
physiological events of oocyte maturation. The system uses cAMP modulators in two steps …
physiological events of oocyte maturation. The system uses cAMP modulators in two steps …
Approaches to oocyte meiotic arrest in vitro and impact on oocyte developmental competence
D Richani, RB Gilchrist - Biology of Reproduction, 2022 - academic.oup.com
Oocytes are maintained in a state of meiotic arrest following the first meiotic division until
ovulation is triggered. Within the antral follicle, meiotic arrest is actively suppressed in a …
ovulation is triggered. Within the antral follicle, meiotic arrest is actively suppressed in a …
[HTML][HTML] The combination of rolipram and cilostamide improved the developmental competence of cloned porcine embryos
BM Tanga, X Fang, S Bang, C Seo, H Kang, D Cha… - Scientific Reports, 2023 - nature.com
In vitro maturation of porcine oocytes is characterized by asynchronous cytoplasmic and
nuclear maturation, leading to less competent oocytes supporting embryo development. The …
nuclear maturation, leading to less competent oocytes supporting embryo development. The …
[HTML][HTML] Circular RNA profiling in the oocyte and cumulus cells reveals that circARMC4 is essential for porcine oocyte maturation
Z Cao, D Gao, T Xu, L Zhang, X Tong, D Zhang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Thousands of circular RNAs (circRNAs) have been recently discovered in cumulus cells and
oocytes from several species. However, the expression and function of circRNA during …
oocytes from several species. However, the expression and function of circRNA during …
[HTML][HTML] Mesenchymal stem cell-derived apoptotic vesicles ameliorate impaired ovarian folliculogenesis in polycystic ovary syndrome and ovarian aging by targeting …
Y Fu, M Zhang, B Sui, FF Yuan, W Zhang, Y Weng… - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: It has been emergingly recognized that apoptosis generates plenty of
heterogeneous apoptotic vesicles (apoVs), which play a pivotal role in the maintenance of …
heterogeneous apoptotic vesicles (apoVs), which play a pivotal role in the maintenance of …
[HTML][HTML] Enhancing oocyte competence with milrinone as a phosphodiesterase 3A inhibitor to improve the development of porcine cloned embryos
The objective of this study was to investigate the effect of milrinone supplementation as a
phosphodiesterase 3A inhibitor during in vitro maturation (IVM) to coordinate the …
phosphodiesterase 3A inhibitor during in vitro maturation (IVM) to coordinate the …
In vitro production of small ruminant embryos: Latest improvements and further research
JMG Souza-Fabjan, RITP Batista… - Reproduction …, 2021 - CSIRO Publishing
This review presents the latest advances in and main obstacles to the application of in vitro
embryo production (IVEP) systems in small ruminants. This biotechnology is an extremely …
embryo production (IVEP) systems in small ruminants. This biotechnology is an extremely …
Role of phosphoinositide 3-kinase/protein kinase B/phosphatase and tensin homologue (PI3K/AKT/PTEN) pathway inhibitors during in vitro maturation of mammalian …
LP Alcaráz, L Prellwitz, G Alves, JMG Souza-Fabjan… - Theriogenology, 2022 - Elsevier
Modulation of phosphoinositide 3-kinase/protein kinase B/phosphatase and tensin
homologue (PI3K/AKT/PTEN) pathway in mammals yields mixed results. A deep …
homologue (PI3K/AKT/PTEN) pathway in mammals yields mixed results. A deep …
Conditions to optimise the developmental competence of immature equine oocytes
ES Metcalf, KR Masterson, D Battaglia… - Reproduction …, 2020 - CSIRO Publishing
Optimising the developmental potential of immature equine oocytes and in vitro-produced
(IVP) embryos was explored through modifications of established media and holding …
(IVP) embryos was explored through modifications of established media and holding …