On the use of tandem mass spectra acquired from samples of evolutionarily distant organisms to validate methods for false discovery rate estimation

D Madej, H Lam - Proteomics, 2024 - Wiley Online Library
Estimating the false discovery rate (FDR) of peptide identifications is a key step in
proteomics data analysis, and many methods have been proposed for this purpose …

Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment

B Wen, J Freestone, M Riffle, MJ MacCoss, WS Noble… - bioRxiv, 2024 - biorxiv.org
A pressing statistical challenge in the field of mass spectrometry proteomics is how to assess
whether a given software tool provides accurate error control. Each software tool for …

Deep learning algorithms for database-driven peptide search

J Zumer - 2024 - papyrus.bib.umontreal.ca
Modern proteomics–the large-scale analysis of proteins (Graves and Haystead, 2002)–
relies heavily on the analysis of complex raw experimental, time series-like data. In a typical …