The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Viruses are obligate intracellular parasites. Despite their dependence on host cells, viruses
are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked …

DNA viruses have a major influence on the ecology and evolution of cellular organisms,,–,
but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a …

The discovery of eukaryotic giant viruses has transformed our understanding of the limits of
viral complexity, but the extent of their encoded metabolic diversity remains unclear. Here …

Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

Abstract The Nucleocytoplasmic Large DNA Viruses (NCLDV) of eukaryotes (proposed
order “Megavirales”) comprise an expansive group of eukaryotic viruses that consists of the …

Recent discoveries of new large DNA viruses reveal high diversity in their morphologies,
genetic repertoires, and replication strategies. Here, we report the novel features of …

Giant and large eukaryotic double-stranded DNA viruses from the Nucleo-Cytoplasmic
Large DNA Virus (NCLDV) assemblage represent a remarkably diverse and potentially …

One quarter of the Northern hemisphere is underlain by permanently frozen ground, referred
to as permafrost. Due to climate warming, irreversibly thawing permafrost is releasing …