Inter-tissue communication in cancer cachexia

JM Argilés, B Stemmler, FJ López-Soriano… - Nature Reviews …, 2019 - nature.com
Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …

Cancer cachexia: mediators, signaling, and metabolic pathways

KCH Fearon, DJ Glass, DC Guttridge - Cell metabolism, 2012 - cell.com
Cancer cachexia is characterized by a significant reduction in body weight resulting
predominantly from loss of adipose tissue and skeletal muscle. Cachexia causes reduced …

Adipose tissue: between the extremes

A Vegiopoulos, M Rohm, S Herzig - The EMBO journal, 2017 - embopress.org
Adipose tissue represents a critical component in healthy energy homeostasis. It fulfills
important roles in whole‐body lipid handling, serves as the body's major energy storage …

Cancer cachexia: more than skeletal muscle wasting

SF Schmidt, M Rohm, S Herzig, MB Diaz - Trends in cancer, 2018 - cell.com
Cancer cachexia is a multifactorial condition characterized by body weight loss that
negatively affects quality of life and survival of patients with cancer. Despite the clinical …

Energy metabolism in cachexia

M Rohm, A Zeigerer, J Machado, S Herzig - EMBO reports, 2019 - embopress.org
Cachexia is a wasting disorder that accompanies many chronic diseases including cancer
and results from an imbalance of energy requirements and energy uptake. In cancer …

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance

P Arner, D Langin - Trends in Endocrinology & Metabolism, 2014 - cell.com
Triglycerides in adipose tissue are rapidly mobilized during times of energy needs via
lipolysis, a catabolic process that plays important role in whole body triglyceride turnover …

Tumor markers for hepatocellular carcinoma

YJ Zhao, Q Ju, GC Li - Molecular and clinical oncology, 2013 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with a high
rate of morbidity and mortality. HCC affects approximately one million individuals annually …

[HTML][HTML] Tumor macroenvironment and metabolism

W Al-Zhoughbi, J Huang, GS Paramasivan, H Till… - Seminars in …, 2014 - Elsevier
In this review we introduce the concept of the tumor macroenvironment and explore it in the
context of metabolism. Tumor cells interact with the tumor microenvironment including …

Biomarkers of cancer cachexia

A Loumaye, JP Thissen - Clinical biochemistry, 2017 - Elsevier
Cachexia is a complex multifactorial syndrome, characterized by loss of skeletal muscle and
fat mass, which affects the majority of advanced cancer patients and is associated with poor …

Zinc and the innovative zinc-α2-glycoprotein adipokine play an important role in lipid metabolism: a critical review

M Banaszak, I Górna, J Przysławski - Nutrients, 2021 - mdpi.com
Numerous studies indicate that zinc and the new zinc-related adipokine, zinc-α2-
glycoprotein (ZAG), are involved in lipid metabolism. Excess body fat lowers blood …