Functional circuitry of the retina
The mammalian retina is an important model system for studying neural circuitry: Its role in
sensation is clear, its cell types are relatively well defined, and its responses to natural …
sensation is clear, its cell types are relatively well defined, and its responses to natural …
The dynamic receptive fields of retinal ganglion cells
S Wienbar, GW Schwartz - Progress in retinal and eye research, 2018 - Elsevier
Retinal ganglion cells (RGCs) were one of the first classes of sensory neurons to be
described in terms of a receptive field (RF). Over the last six decades, our understanding of …
described in terms of a receptive field (RF). Over the last six decades, our understanding of …
Cellular and circuit mechanisms shaping the perceptual properties of the primate fovea
The fovea is a specialized region of the retina that dominates the visual perception of
primates by providing high chromatic and spatial acuity. While the foveal and peripheral …
primates by providing high chromatic and spatial acuity. While the foveal and peripheral …
Sidekick 2 directs formation of a retinal circuit that detects differential motion
In the mammalian retina, processes of approximately 70 types of interneurons form specific
synapses on roughly 30 types of retinal ganglion cells (RGCs) in a neuropil called the inner …
synapses on roughly 30 types of retinal ganglion cells (RGCs) in a neuropil called the inner …
APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans
AV Tkatchenko, TV Tkatchenko, JA Guggenheim… - PLoS …, 2015 - journals.plos.org
Myopia is the most common vision disorder and the leading cause of visual impairment
worldwide. However, gene variants identified to date explain less than 10% of the variance …
worldwide. However, gene variants identified to date explain less than 10% of the variance …
Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types
S Wienbar, GW Schwartz - Neuron, 2022 - cell.com
Retinal ganglion cells (RGCs) are the spiking projection neurons of the eye that encode
different features of the visual environment. The circuits providing synaptic input to different …
different features of the visual environment. The circuits providing synaptic input to different …
Circuit mechanisms of a retinal ganglion cell with stimulus-dependent response latency and activation beyond its dendrites
A Mani, GW Schwartz - Current Biology, 2017 - cell.com
Center-surround antagonism has been used as the canonical model to describe receptive
fields of retinal ganglion cells (RGCs) for decades. We describe a newly identified RGC type …
fields of retinal ganglion cells (RGCs) for decades. We describe a newly identified RGC type …
Specific wiring of distinct amacrine cells in the directionally selective retinal circuit permits independent coding of direction and size
A Hoggarth, AJ McLaughlin, K Ronellenfitch… - Neuron, 2015 - cell.com
Local and global forms of inhibition controlling directionally selective ganglion cells
(DSGCs) in the mammalian retina are well documented. It is established that local inhibition …
(DSGCs) in the mammalian retina are well documented. It is established that local inhibition …
Broad thorny ganglion cells: a candidate for visual pursuit error signaling in the primate retina
Functional analyses exist only for a few of the morphologically described primate ganglion
cell types, and their correlates in other mammalian species remain elusive. Here, we …
cell types, and their correlates in other mammalian species remain elusive. Here, we …
Calcium-permeable AMPA receptors on AII amacrine cells mediate sustained signaling in the On-pathway of the primate retina
KA Percival, J Gayet, R Khanjian, WR Taylor… - Cell reports, 2022 - cell.com
Midget and parasol ganglion cells (GCs) represent the major output channels from the
primate eye to the brain. On-type midget and parasol GCs exhibit a higher background spike …
primate eye to the brain. On-type midget and parasol GCs exhibit a higher background spike …