The role of hepatokines in NAFLD

N Stefan, F Schick, AL Birkenfeld, HU Häring, MF White - Cell metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

Obesity and cardiovascular disease: a scientific statement from the American Heart Association

TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …

Gut microbial carbohydrate metabolism contributes to insulin resistance

T Takeuchi, T Kubota, Y Nakanishi, H Tsugawa… - Nature, 2023 - nature.com
Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2
diabetes,. Previous metagenomic studies have described the characteristics of gut …

The changing landscape of atherosclerosis

P Libby - Nature, 2021 - nature.com
Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

Dietary fibre modulates the gut microbiota

P Cronin, SA Joyce, PW O'Toole, EM O'Connor - Nutrients, 2021 - mdpi.com
Dietary fibre has long been established as a nutritionally important, health-promoting food
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …

Obesity phenotypes, diabetes, and cardiovascular diseases

ME Piché, A Tchernof, JP Després - Circulation research, 2020 - Am Heart Assoc
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

R Ross, IJ Neeland, S Yamashita, I Shai… - Nature Reviews …, 2020 - nature.com
Despite decades of unequivocal evidence that waist circumference provides both
independent and additive information to BMI for predicting morbidity and risk of death, this …

Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss

R Kirwan, D McCullough, T Butler, F Perez de Heredia… - GeroScience, 2020 - Springer
The COVID-19 pandemic is an extraordinary global emergency that has led to the
implementation of unprecedented measures in order to stem the spread of the infection …

Resistance training for older adults: position statement from the national strength and conditioning association

MS Fragala, EL Cadore, S Dorgo… - The Journal of …, 2019 - journals.lww.com
Abstract Fragala, MS, Cadore, EL, Dorgo, S, Izquierdo, M, Kraemer, WJ, Peterson, MD, and
Ryan, ED. Resistance training for older adults: position statement from the national strength …

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

IJ Neeland, R Ross, JP Després… - The lancet Diabetes & …, 2019 - thelancet.com
Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …