Causal mapping of human brain function
Mapping human brain function is a long-standing goal of neuroscience that promises to
inform the development of new treatments for brain disorders. Early maps of human brain …
inform the development of new treatments for brain disorders. Early maps of human brain …
Using brain imaging to improve spatial targeting of transcranial magnetic stimulation for depression
Transcranial magnetic stimulation (TMS) is an effective treatment for depression but is
limited in that the optimal therapeutic target remains unknown. Early TMS trials lacked a …
limited in that the optimal therapeutic target remains unknown. Early TMS trials lacked a …
Distinct symptom-specific treatment targets for circuit-based neuromodulation
SH Siddiqi, SF Taylor, D Cooke… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Treatment of different depression symptoms may require different brain
stimulation targets with different underlying brain circuits. The authors sought to identify such …
stimulation targets with different underlying brain circuits. The authors sought to identify such …
Personalized connectivity‐guided DLPFC‐TMS for depression: Advancing computational feasibility, precision and reproducibility
Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex
(DLPFC) is an established treatment for refractory depression, however, therapeutic …
(DLPFC) is an established treatment for refractory depression, however, therapeutic …
The future of brain circuit-targeted therapeutics
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
Precision functional MRI mapping reveals distinct connectivity patterns for depression associated with traumatic brain injury
SH Siddiqi, S Kandala, CD Hacker… - Science translational …, 2023 - science.org
Depression associated with traumatic brain injury (TBI) is believed to be clinically distinct
from primary major depressive disorder (MDD) and may be less responsive to conventional …
from primary major depressive disorder (MDD) and may be less responsive to conventional …
Global connectivity and local excitability changes underlie antidepressant effects of repetitive transcranial magnetic stimulation
Repetitive transcranial magnetic stimulation (rTMS) is a commonly-used treatment for major
depressive disorder (MDD). However, our understanding of the mechanism by which TMS …
depressive disorder (MDD). However, our understanding of the mechanism by which TMS …
Large-scale lesion symptom mapping of depression identifies brain regions for risk and resilience
Understanding neural circuits that support mood is a central goal of affective neuroscience,
and improved understanding of the anatomy could inform more targeted interventions in …
and improved understanding of the anatomy could inform more targeted interventions in …
[HTML][HTML] Personalizing repetitive transcranial magnetic stimulation parameters for depression treatment using multimodal neuroimaging
DCW Klooster, MA Ferguson, PAJM Boon… - Biological Psychiatry …, 2022 - Elsevier
Repetitive transcranial magnetic stimulation (rTMS) is a tool that can be used to administer
treatment for neuropsychiatric disorders such as major depressive disorder, although the …
treatment for neuropsychiatric disorders such as major depressive disorder, although the …
[HTML][HTML] A randomized trial comparing beam F3 and 5.5 cm targeting in rTMS treatment of depression demonstrates similar effectiveness
Abstract Background The Beam F3 and 5.5 cm methods are the two most common targeting
strategies for localizing the left dorsolateral prefrontal cortex (DLPFC) treatment site in …
strategies for localizing the left dorsolateral prefrontal cortex (DLPFC) treatment site in …