Bioinformatics tools and benchmarks for computational docking and 3D structure prediction of RNA-protein complexes
RNA-protein (RNP) interactions play essential roles in many biological processes, such as
regulation of co-transcriptional and post-transcriptional gene expression, RNA splicing …
regulation of co-transcriptional and post-transcriptional gene expression, RNA splicing …
In silico approaches to RNA aptamer design
M Hamada - Biochimie, 2018 - Elsevier
RNA aptamers are ribonucleic acids that bind to specific target molecules. An RNA aptamer
for a disease-related protein has great potential for development into a new drug. However …
for a disease-related protein has great potential for development into a new drug. However …
[HTML][HTML] Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods
The diverse functional cellular roles played by ribonucleic acids (RNA) have emphasized
the need to develop rapid and accurate methodologies to elucidate the relationship between …
the need to develop rapid and accurate methodologies to elucidate the relationship between …
Computational tools to study RNA-protein complexes
RNA is the key player in many cellular processes such as signal transduction, replication,
transport, cell division, transcription, and translation. These diverse functions are …
transport, cell division, transcription, and translation. These diverse functions are …
Modeling the microscopic electrical properties of thrombin binding aptamer (TBA) for label-free biosensors
Aptamers are chemically produced oligonucleotides, able to bind a variety of targets such as
drugs, proteins and pathogens with high sensitivity and selectivity. Therefore, aptamers are …
drugs, proteins and pathogens with high sensitivity and selectivity. Therefore, aptamers are …
RPflex: A Coarse-Grained Network Model for RNA Pocket Flexibility Study
C Zhuo, C Zeng, R Yang, H Liu, Y Zhao - International Journal of …, 2023 - mdpi.com
RNA regulates various biological processes, such as gene regulation, RNA splicing, and
intracellular signal transduction. RNA's conformational dynamics play crucial roles in …
intracellular signal transduction. RNA's conformational dynamics play crucial roles in …
Ribonucleoprotein particles: advances and challenges in computational methods
S Dvir, A Argoetti, Y Mandel-Gutfreund - Current Opinion in Structural …, 2018 - Elsevier
Highlights•Many RBPs escape detection by available experimental techniques.•
Developments in computational algorithms enable the prediction of RBPs that do not …
Developments in computational algorithms enable the prediction of RBPs that do not …
Partner‐specific prediction of RNA‐binding residues in proteins: A critical assessment
RNA‐protein interactions play essential roles in regulating gene expression. While some
RNA‐protein interactions are “specific”, that is, the RNA‐binding proteins preferentially bind …
RNA‐protein interactions are “specific”, that is, the RNA‐binding proteins preferentially bind …
[PDF][PDF] Homology modeling of the complex between the Repressor of Primer protein and its cognate RNA kissing complex
D Nikolopoulou - 2022 - utopia.duth.gr
The ROP protein is a dimeric protein with an α-helix bundle conformation that is found in
bacteria. ROP protein is involved in the replication regulation mechanism of the …
bacteria. ROP protein is involved in the replication regulation mechanism of the …