In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …

The key players of calcium (Ca2+) homeostasis and Ca2+ signal generation, which are
Ca2+ channels, Ca2+/H+ antiporters, and Ca2+-ATPases, are present in all fungi. Their …

The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …

Cryptococcus neoformans, an opportunistic yeast pathogen, relies on a complex network of
stress response pathways that allow for proliferation in the host. In Saccharomyces …

Due to lifespan extension and changes in global climate, the increase in mycoses caused by
primary and opportunistic fungal pathogens is now a global concern. Despite increasing …

Flippases are key regulators of membrane asymmetry and secretory mechanisms. Vesicular
polysaccharide secretion is essential for the pathogenic mechanisms of Cryptococcus …

Cryptococcus neoformans is an opportunistic fungal pathogen that at its peak epidemic
levels caused an estimated million cases of cryptococcal meningitis per year worldwide …

Abstract The Ca2+/calmodulin-dependent protein phosphatase calcineurin orchestrates
sexual reproduction, stress responses, and virulence via branched downstream pathways in …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the …

The opportunistic fungal pathogen Aspergillus fumigatus, which is one of the primary
airborne ascomycete pathogens and allergens worldwide, causes invasive fungal infections …