Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …

Adolescence encompasses a sensitive developmental period of enhanced clinical
vulnerability to nicotine, tobacco, and e‐cigarettes. While there are sociocultural influences …

Adolescence is a developmental period in which the mesolimbic dopaminergic “reward”
circuitry of the brain, including the nucleus accumbens (NAc), undergoes significant …

It has been hypothesized that reward‐seeking and impulsivity develop along different
timetables and have different neural underpinnings, and that the difference in their …

To successfully negotiate the developmental transition between youth and adulthood,
adolescents must maneuver this often stressful period while acquiring skills necessary for …

Adolescence is a developmental period characterized by suboptimal decisions and actions
that give rise to an increased incidence of unintentional injuries and violence, alcohol and …

The prevailing view in the field of adolescent brain development is that heightened activity in
the mesolimbic dopaminergic reward system serves as a liability, orienting adolescents …

This article proposes a framework for theory and research on risk-taking that is informed by
developmental neuroscience. Two fundamental questions motivate this review. First, why …

Early life stress–including experience of child maltreatment, neglect, separation from or loss
of a parent, and other forms of adversity–increases lifetime risk of mood, anxiety, and …

It has been hypothesized that sensation seeking and impulsivity, which are often conflated,
in fact develop along different timetables and have different neural underpinnings, and that …