Immune Checkpoint Blockade Delays Cancer and Extends Survival in Murine DNA Polymerase Mutator Syndromes

A Sawant, F Shi, EC Lopes, Z Hu, S Abdelfattah, J Baul… - bioRxiv, 2024 - biorxiv.org
Mutations in polymerases Pold1 and Pole exonuclease domains in humans are associated
with increased cancer incidence, elevated tumor mutation burden (TMB) and response to …