Tissue engineered skin substitutes for wound healing have evolved tremendously over the
last couple of years. New advances have been made toward developing skin substitutes …

Collagen, the most abundant extracellular matrix protein in animal kingdom belongs to a
family of fibrous proteins, which transfer load in tissues and which provide a highly …

Biologic scaffold materials composed of extracellular matrix (ECM) are typically derived by
processes that involve decellularization of tissues or organs. Preservation of the complex …

Current advances in basic stem cell research and tissue engineering augur well for the
development of improved cultured skin tissue substitutes: a class of products that is still …

Background The loss of a normal airway is devastating. Attempts to replace large airways
have met with serious problems. Prerequisites for a tissue-engineered replacement are a …

The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

The goal of this study was the production of a decellularized kidney scaffold with structural,
mechanical, and physiological properties necessary for engineering basic renal structures in …

Small intestine submucosa (SIS) has emerged as one of a number of naturally derived
extracellular matrix (ECM) biomaterials currently in clinical use. In addition to clinical …

Two years ago we performed the first clinical successful transplantation of a fully tissue
engineered trachea. Despite the clinically positive outcome, the graft production took almost …

Acellular cartilage can provide a native extracellular matrix for cartilage engineering.
However, it is difficult for cells to migrate into acellular cartilage because of its non-porous …