This review highlights recent findings about the role that endothelial glycocalyx and
caveolae play in vascular homeostasis. We describe the structure, synthesis, and function of …

Endothelial dysfunction and consequent vasoconstriction are a common condition in
patients with hypertension and other cardiovascular diseases. Endothelial cells produce and …

Ellagic acid is described as having antioxidant and antiproliferative properties. Hence, it was
hypothesized that ellagic acid could improve cardiovascular damage caused by …

Caveolae are plasma membrane invaginations enriched with high cholesterol and
sphingolipid content; they also contain caveolin proteins in their structure. Endothelial nitric …

Background Two-kidney-one-clip (2K-1C) rats develop renovascular hypertension
associated with endothelial dysfunction and elevated levels of oxidative stress. The role of …

During three decades, an enormous number of studies have demonstrated the critical role of
nitric oxide (NO) as a second messenger engaged in the activation of many systems …

Nitric oxide (NO) donors are substances that can release NO. Vascular relaxation induction
is among the several functions of NO, and the administration of NO donors is a …

Impaired relaxation induced by the new nitric oxide (NO) donor [Ru (NH. NHq)(terpy) NO+]
3+(TERPY) has been observed in the aortic rings from renal hypertensive rats (2K-1C). An …

Drugs that release nitric oxide (NO) usually have limitations due to their harmful effects.
Sodium nitroprusside (SNP) induces a rapid hypotension that leads to reflex tachycardia …

Recently, remarkable biological functions have been attributed to nitric oxide (NO) as
responsible to mediate neuronal communication, blood vessel modulation, and immune …