A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration

PY Hwang, J Mathur, Y Cao, J Almeida, J Ye… - Developmental cell, 2023 - cell.com
Carcinoma dissemination can occur when heterogeneous tumor and tumor-stromal cell
clusters migrate together via collective migration. Cells at the front lead and direct collective …

[HTML][HTML] Transcriptional intra-tumour heterogeneity predicted by deep learning in routine breast histopathology slides provides independent prognostic information

Y Wang, MA Ali, J Vallon-Christersson… - European Journal of …, 2023 - Elsevier
Background Intra-tumour heterogeneity (ITH) causes diagnostic challenges and increases
the risk for disease recurrence. Quantification of ITH is challenging and has not been …

Predictive factors for relapse in triple-negative breast cancer patients without pathological complete response after neoadjuvant chemotherapy

A Toss, M Venturelli, M Civallero, C Piombino… - Frontiers in …, 2022 - frontiersin.org
Introduction Triple-negative breast cancer (TNBC) patients who do not obtain pathological
complete response (pCR) after neoadjuvant chemotherapy (NACT) present higher rate of …

Breast tumor IGF1R regulates cell adhesion and metastasis: alignment of mouse single cell and human breast cancer transcriptomics

AE Obr, JJ Bulatowicz, YJ Chang, V Ciliento… - Frontiers in …, 2022 - frontiersin.org
Introduction The acquisition of a metastatic phenotype is the critical event that determines
patient survival from breast cancer. Several receptor tyrosine kinases have functions both in …

Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins

M Xu, C Liu, L Pu, J Lai, J Li, Q Ning… - Experimental …, 2021 - journals.sagepub.com
Cadherins form connection between cells, facilitate communication, and serve as essential
agents in the progression of multiple cancers. Over 100 cadherins have been identified and …

Identification and validation of genes associated with copper death in oral squamous cell carcinoma based on machine learning and weighted gene co-expression …

M Zhang, Q Li, W Zhang, Y Yang, J Gu… - Journal of Stomatology …, 2023 - Elsevier
Objective To identify copper-induced death-associated hub genes in oral squamous cell
carcinoma (OSCC) and understand their functional and biological significance using …

3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer

C São José, C Pereira, M Ferreira, A André, H Osório… - Biology, 2023 - mdpi.com
Simple Summary The cell architecture is created and maintained via adhesion molecules,
called cadherins, that keep similar cells bound to each other. E-cadherin is a cadherin …

[HTML][HTML] Hsa_circ_0023179 modulated the processes of proliferation, apoptosis, and EMT in non-small-cell lung cancer cells via the miR-615-5p/CDH3 axis

Q Guo, M Zheng, C Zhu, B Wu - Biomolecules and …, 2025 - pmc.ncbi.nlm.nih.gov
Circular RNA (circRNA) has been widely studied as a competitive endogenous RNA
targeting microRNA (miRNA)/messenger RNA to regulate cancer progression. However, the …

Slug 通过下调CDH3/β-catenin/C-myc 表达抑制宫颈癌细胞增殖

刘宪, 张燕茹, 陈茜, 冯倩, 王海燕, 崔南 - 肿瘤防治研究, 2021 - zlfzyj.com
Slug通过下调CDH3/β-catenin/C-myc表达抑制宫颈癌细胞增殖刘宪, 张燕茹, 陈茜, 冯倩, 王海燕
, 崔南引 Page 1 Slug通过下调CDH3/β-catenin/C-myc表达抑制宫颈癌细胞增殖 刘宪, 张燕茹 …

Biomarkers of Aggressive Thyroid Cancer

GJ Xu - 2023 - search.proquest.com
Genomic and transcriptomic analysis have revolutionized our understanding of many
cancers. However, genomic understanding of thyroid cancer has lagged behind other …