[HTML][HTML] Molecular mechanisms of platinum‑based chemotherapy resistance in ovarian cancer

L Yang, HJ Xie, YY Li, X Wang… - Oncology …, 2022 - build.spandidos-publications.com
Cisplatin is one of the most effective chemotherapy drugs for ovarian cancer, but resistance
is common. The initial response to platinum‑based chemotherapy is as high as 80%, but in …

Biomaterial-based platforms for modulating immune components against cancer and cancer stem cells

N Desai, U Hasan, K Jeyashree, R Mani, M Chauhan… - Acta Biomaterialia, 2023 - Elsevier
Immunotherapy involves the therapeutic alteration of the patient's immune system to identify,
target, and eliminate cancer cells. Dendritic cells, macrophages, myeloid-derived …

Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets

J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …

Epithelial ovarian cancer: A five year review

C Arnaoutoglou, K Dampala, C Anthoulakis… - Medicina, 2023 - mdpi.com
Ovarian cancer is a malignant disease that affects thousands of patients every year.
Currently, we use surgical techniques for early-stage cancer and chemotherapy treatment …

Targeting the tumour microenvironment in platinum-resistant ovarian cancer

M Cummings, C Freer, NM Orsi - Seminars in cancer biology, 2021 - Elsevier
Ovarian cancer typically presents at an advanced stage, and although the majority of cases
initially respond well to platinum-based therapies, chemoresistance almost always occurs …

Epidemiological trends and risk factors of gynecological cancers: an update

V Keyvani, N Kheradmand, ZN Navaei, S Mollazadeh… - Medical Oncology, 2023 - Springer
Gynecological cancers, the most common cancer among women worldwide, disrupt the
function of women's reproductive system, significantly impacting the quality of life. The …

Cancer Stem Cell Markers—Clinical Relevance and Prognostic Value in High-Grade Serous Ovarian Cancer (HGSOC) Based on The Cancer Genome Atlas Analysis

N Iżycka, MP Zaborowski, Ł Ciecierski, K Jaz… - International Journal of …, 2023 - mdpi.com
Cancer stem cells (CSCs) may contribute to an increased risk of recurrence in ovarian
cancer (OC). Further research is needed to identify associations between CSC markers and …

[HTML][HTML] Progesterone receptor membrane component (PGRMC) 1 and PGRMC2 and their roles in ovarian and endometrial cancer

JJ Peluso, JK Pru - Cancers, 2021 - mdpi.com
Simple Summary Ovarian and endometrial cancers occur frequently and can be lethal.
Recently, progesterone receptor membrane component (PGRMC) 1 and PGRMC2 have …

The toll-like receptor 4 polymorphism Asp299Gly is associated with an increased risk of ovarian cancer

KD Kania, D Haręża, JR Wilczyński, M Wilczyński… - Cells, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common cancers threatening women's lives around
the world. Epithelial ovarian tumors represent the most common ovarian neoplasms. Most …

Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells

H Koltai, N Shalev - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most lethal gynecological malignancy. Cancer stem
cells have been implicated in tumor initiation, progression, and invasion, as well as tumor …