Knowledge of the interactions between nanoparticles (NPs) and cell membranes is of great
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …

The intestinal epithelium forms a highly dynamic and selective barrier that controls
absorption of fluid and solutes while restricting pathogen access to underlying tissues …

Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome
into the host cell. While some viruses fuse with the plasma membrane, many viruses are …

The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

The intestinal epithelium forms a key protective barrier that separates internal organs from
the harmful environment of the gut lumen. Increased permeability of the gut barrier is a …

The current paradigm of inflammatory bowel diseases (IBD), both Crohn's disease (CD) and
ulcerative colitis (UC), involves the interaction between environmental factors in the …

Cytokines play a crucial role in the modulation of inflammatory response in the
gastrointestinal tract. Pro-inflammatory cytokines including tumor necrosis factor-α, interferon …

Evaluation of the human genome suggests that all members of the connexin family of gap-
junction proteins have now been successfully identified. This large and diverse family of …