RNA therapeutics have had a tremendous impact on medicine, recently exemplified by the
rapid development and deployment of mRNA vaccines to combat the COVID-19 pandemic …

The ability to sense and respond to infection is essential for life. Viral infection produces
double-stranded RNAs (dsRNAs) that are sensed by proteins that recognize the structure of …

Simple Summary Multiple myeloma (MM), a plasma cell neoplasm, is an incurable
hematological malignancy. Gain/amplification of chromosome arm 1q21 (1q21+) is the most …

Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs)
in the bone marrow (BM). The amplification of 1q21 is one of the most common cytogenetic …

Although the route to generate microRNAs (miRNAs) is often depicted as a linear series of
sequential and constitutive cleavages, we now appreciate multiple alternative pathways as …

Mitosis detection is an important step in pathology procedures in the context of cancer
diagnosis and prognosis. Prevalent process for this task is by manually observing …

Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional
process related to a multitude of cellular and molecular activities. However, systematic …

Stau1 is a pluripotent RNA-binding protein that is responsible for the post-transcriptional
regulation of a multitude of transcripts. Here, we observed that lung cancer patients with a …

Esophageal cancer (EC) is a common malignant disease in eastern countries. However, a
study of the metabolomic characteristics associated with other biological factors in …

Gastric cancer (GC) is one of the deadliest cancers, and long noncoding RNAs (lncRNAs)
have been reported to be the important regulators during the occurrence and development …