A narrative review of the molecular epidemiology and laboratory surveillance of vaccine preventable bacterial meningitis agents: Streptococcus pneumoniae …

RSW Tsang - Microorganisms, 2021 - mdpi.com
This narrative review describes the public health importance of four most common bacterial
meningitis agents, Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus …

Puzzling over the pneumococcal pangenome

NL Hiller, R Sá-Leão - Frontiers in microbiology, 2018 - frontiersin.org
The Gram positive bacterium Streptococcus pneumoniae (pneumococcus) is a major human
pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and …

Longitudinal characterization of nasopharyngeal colonization with Streptococcus pneumoniae in a South African birth cohort post 13-valent pneumococcal conjugate …

FS Dube, J Ramjith, S Gardner-Lubbe, P Nduru… - Scientific reports, 2018 - nature.com
Monitoring changes in pneumococcal carriage is key to understanding vaccination-induced
shifts in the ecology of carriage and impact on health. We longitudinally investigated …

Molecular characterization of predominant Streptococcus pneumoniae serotypes causing invasive infections in Canada: the SAVE study, 2011–15

AR Golden, HJ Adam, JA Karlowsky… - Journal of …, 2018 - academic.oup.com
Objectives This study characterized the 11 most predominant serotypes of invasive
Streptococcus pneumoniae infections collected by the annual SAVE study in Canada …

Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group

MW Pletz, AV Jensen, C Bahrs, C Davenport… - Respiratory …, 2022 - Springer
Introduction Despite improvements in medical science and public health, mortality of
community-acquired pneumonia (CAP) has barely changed throughout the last 15 years …

Circulating clonal complexes and sequence types of Streptococcus pneumoniae serotype 19A worldwide: the importance of multidrug resistance: a systematic …

Y Ruiz García, J Nieto Guevara, P Izurieta… - Expert Review of …, 2021 - Taylor & Francis
Introduction Streptococcus pneumoniae is a major cause of morbidity and mortality,
especially amongst young children and the elderly. Childhood implementation of …

Pre-vaccine serotype composition within a lineage signposts its serotype replacement–a carriage study over 7 years following pneumococcal conjugate vaccine use …

RA Gladstone, V Devine, J Jones… - Microbial …, 2017 - microbiologyresearch.org
Serotype replacement has been reported in carriage and disease after pneumococcal
conjugate vaccine (PCV) introductions in the UK and globally. We previously described …

High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland

JP Rodriguez-Ruiz, BB Xavier, W Stöhr… - BMC microbiology, 2024 - Springer
Background Streptococcus pneumoniae is a global cause of community-acquired
pneumonia (CAP) and invasive disease in children. The CAP-IT trial (grant No. 13/88/11; …

Molecular characterization of Latin American invasive Streptococcus pneumoniae serotype 19A isolates

J Moreno, C Duarte, AP Cassiolato, GC Chacón… - Vaccine, 2020 - Elsevier
Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, especially
among children and the elderly. S. pneumoniae serotype 19A has emerged as a major …

The pneumococcal serotype 15C capsule is partially O-acetylated and allows for limited evasion of 23-valent pneumococcal polysaccharide vaccine-elicited anti …

BL Spencer, AT Shenoy, CJ Orihuela… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
As a species, Streptococcus pneumoniae (the pneumococcus) utilizes a diverse array of
capsular polysaccharides to evade the host. In contrast to large variations in sugar …