In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

The relationship between periodontitis and systemic diseases, notably including
atherosclerosis and diabetes, has been studied for several years. Porphyromonas …

Porphyromonas gingivalis is a gram-negative, anaerobic bacterium that lives in the oral
cavity. It is an integral part of the oral microbiome, which includes more than 500 types of …

Atherosclerosis (AS) is a chronic inflammatory disease, involving a pathological process of
endothelial dysfunction, lipid deposition, plaque rupture, and arterial occlusion, and is one of …

Periodontitis is a chronic inflammatory condition that destroys the tooth‐supporting tissues
and eventually leads to tooth loss. As one of the most prevalent oral conditions, periodontitis …

Background: Porphyromonas gingivalis (P. gingivalis) and its gingipain virulence factors
have been identified as pathogenic effectors in Alzheimer's disease (AD). In a recent study …

Extensive research in humans and animal models has begun to unravel the complex
mechanisms that drive the immunopathogenesis of periodontitis. Neutrophils mount an early …

Immune therapeutic exosomes, derived exogenously from dendritic cells (DCs), the
'directors' of the immune response, are receiving favorable safety and tolerance profiles in …

Research in recent years has focused significantly on the role of selective macroautophagy
in targeting intracellular pathogens for lysosomal degradation, a process termed xenophagy …