Background In nephrotic syndrome protein leaks from blood into the urine through the
glomeruli resulting in hypoproteinaemia and generalised oedema. While most children with …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Background About 80% of children with steroid‐sensitive nephrotic syndrome (SSNS) have
relapses. Of these children, half relapse frequently, and are at risk of adverse effects from …

Levamisole has been considered the least toxic and least expensive steroid-sparing drug for
preventing relapses of steroid-sensitive idiopathic nephrotic syndrome (SSINS). However …

Steroid sensitive nephrotic syndrome is one of the most common pediatric glomerular
diseases. Unfortunately, it follows a relapsing and remitting course in the majority of cases …

Immunosuppressive agents in childhood nephrotic syndrome: A meta-analysis of
randomized trials. Background Many children with steroid-sensitive nephrotic syndrome …

Using data from systematic reviews and randomised controlled trials, the evidence for
managing steroid sensitive nephrotic syndrome (SSNS) is reviewed. In the initial episode …

Objective Levamisole (LEV) has been used successfully on an alternate-day regime of 2.5
mg/kg in steroid-dependant nephrotic syndrome (SDNS) to maintain remission. This pilot …

Among the different drugs used for sparing steroids in steroid-sensitive nephrotic syndrome
(SSNS) with frequent relapses and steroid dependency, levamisole is the least toxic and the …

This was a controlled prospective study on the use of an immunomodulator drug,
levamisole, in the treatment of frequently relapsing, steroid-dependent (FR/SD) idiopathic …