[HTML][HTML] Mechanisms governing anaphylaxis: inflammatory cells, mediators, endothelial gap junctions and beyond
SMT Nguyen, CP Rupprecht, A Haque… - International journal of …, 2021 - mdpi.com
Anaphylaxis is a severe, acute, life-threatening multisystem allergic reaction resulting from
the release of a plethora of mediators from mast cells culminating in serious respiratory …
the release of a plethora of mediators from mast cells culminating in serious respiratory …
[HTML][HTML] Endothelial Ca2+ Signaling, Angiogenesis and Vasculogenesis: Just What It Takes to Make a Blood Vessel
It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …
[HTML][HTML] Reactive Oxygen Species and Endothelial Ca2+ Signaling: Brothers in Arms or Partners in Crime?
An increase in intracellular Ca2+ concentration ([Ca2+] i) controls virtually all endothelial
cell functions and is, therefore, crucial to maintain cardiovascular homeostasis. An aberrant …
cell functions and is, therefore, crucial to maintain cardiovascular homeostasis. An aberrant …
[HTML][HTML] Transient receptor potential ankyrin 1 (TRPA1) mediates reactive oxygen species-induced Ca2+ entry, mitochondrial dysfunction, and caspase-3/7 activation …
P Faris, A Rumolo, G Pellavio, M Tanzi… - Cell Death …, 2023 - nature.com
Colorectal carcinoma (CRC) represents the fourth most common cancer worldwide and is
the third most common cause of malignancy-associated mortality. Distant metastases to the …
the third most common cause of malignancy-associated mortality. Distant metastases to the …
[HTML][HTML] Therapeutic potential of endothelial colony-forming cells in ischemic disease: strategies to improve their regenerative efficacy
Cardiovascular disease (CVD) comprises a range of major clinical cardiac and circulatory
diseases, which produce immense health and economic burdens worldwide. Currently …
diseases, which produce immense health and economic burdens worldwide. Currently …
[HTML][HTML] GABAA and GABAB Receptors Mediate GABA-Induced Intracellular Ca2+ Signals in Human Brain Microvascular Endothelial Cells
Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid
(GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by …
(GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by …
[HTML][HTML] The Molecular Heterogeneity of Store-Operated Ca2+ Entry in Vascular Endothelial Cells: The Different roles of Orai1 and TRPC1/TRPC4 Channels in the Transition …
F Moccia, V Brunetti, A Perna, G Guerra… - International journal of …, 2023 - mdpi.com
Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1, 4, 5-
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …
[HTML][HTML] Allyl Isothiocianate Induces Ca2+ Signals and Nitric Oxide Release by Inducing Reactive Oxygen Species Production in the Human Cerebrovascular …
R Berra-Romani, V Brunetti, G Pellavio, T Soda… - Cells, 2023 - mdpi.com
Nitric oxide (NO) represents a crucial mediator to regulate cerebral blood flow (CBF) in the
human brain both under basal conditions and in response to somatosensory stimulation. An …
human brain both under basal conditions and in response to somatosensory stimulation. An …
NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain …
The excitatory neurotransmitter glutamate gates post-synaptic N-methyl-d-aspartate (NMDA)
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric oxide …
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric oxide …
[HTML][HTML] Targeting endolysosomal two-pore channels to treat cardiovascular disorders in the novel COronaVIrus Disease 2019
Emerging evidence hints in favor of a life-threatening link between severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) and the cardiovascular system. SARS-CoV-2 …
syndrome coronavirus type 2 (SARS-CoV-2) and the cardiovascular system. SARS-CoV-2 …