Plant secondary metabolites (PSMs) play many roles including defense against pathogens,
pests, and herbivores; response to environmental stresses, and mediating organismal …

Advances in high-throughput sequencing (HTS) have fostered rapid developments in the
field of microbiome research, and massive microbiome datasets are now being generated …

Grazing represents the most extensive use of land worldwide. Yet its impacts on ecosystem
services remain uncertain because pervasive interactions between grazing pressure …

Factors driving microbial community composition and diversity are well established but the
relationship with microbial functioning is poorly understood, especially at large scales. We …

Soils are the foundation of all terrestrial ecosystems. However, unlike for plants and animals,
a global assessment of hotspots for soil nature conservation is still lacking. This hampers our …

Microbial amplicon sequencing studies are an important tool in biological and biomedical
research. Widespread 16S rRNA gene microbial surveys have shed light on the structure of …

SARS-CoV-2 enters host cells through an interaction between the spike glycoprotein and
the angiotensin converting enzyme 2 (ACE2) receptor. Directly preventing this interaction …

Recent advances have made it possible to analyze high-throughput marker-gene
sequencing data without resorting to the customary construction of molecular operational …

Amplicon sequencing of tags such as 16S and ITS ribosomal RNA is a popular method for
investigating microbial populations. In such experiments, sequence errors caused by PCR …

Abstract Motivation The 16S ribosomal RNA (rRNA) gene is widely used to survey microbial
communities. Sequences are often clustered into Operational Taxonomic Units (OTUs) as …