Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Challenges of unculturable bacteria: environmental perspectives

A Bodor, N Bounedjoum, GE Vincze… - … Science and Bio …, 2020 - Springer
Environmental biotechnology offers several promising techniques for the rehabilitation of
polluted environments. The modern industrialized world presents novel challenges to the …

AI-2-mediated signalling in bacteria

CS Pereira, JA Thompson… - FEMS microbiology …, 2013 - academic.oup.com
Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Indole as an intercellular signal in microbial communities

JH Lee, J Lee - FEMS microbiology reviews, 2010 - academic.oup.com
Bacteria can utilize signal molecules to coordinate their behavior to survive in dynamic
multispecies communities. Indole is widespread in the natural environment, as a variety of …

Bacterial quorum-sensing network architectures

WL Ng, BL Bassler - Annual review of genetics, 2009 - annualreviews.org
Quorum sensing is a cell-cell communication process in which bacteria use the production
and detection of extracellular chemicals called autoinducers to monitor cell population …

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways

WRJD Galloway, JT Hodgkinson, SD Bowden… - Chemical …, 2011 - ACS Publications
Numerous species of bacteria employ a mechanism of intercellular communication known
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …

“It takes a village”: mechanisms underlying antimicrobial recalcitrance of polymicrobial biofilms

G Orazi, GA O'Toole - Journal of Bacteriology, 2019 - Am Soc Microbiol
Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …

Mechanisms of bacterial tolerance and persistence in the gastrointestinal and respiratory environments

R Trastoy, T Manso, L Fernández-García… - Clinical microbiology …, 2018 - Am Soc Microbiol
Pathogens that infect the gastrointestinal and respiratory tracts are subjected to intense
pressure due to the environmental conditions of the surroundings. This pressure has led to …

An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae

M Huber, A Lippegaus, S Melamed, M Siemers… - Nature …, 2022 - nature.com
Small regulatory RNAs (sRNAs) acting in concert with the RNA chaperone Hfq are prevalent
in many bacteria and typically act by base-pairing with multiple target transcripts. In the …

Specificity in two-component signal transduction pathways

MT Laub, M Goulian - Annu. Rev. Genet., 2007 - annualreviews.org
Two-component signal transduction systems enable bacteria to sense, respond, and adapt
to a wide range of environments, stressors, and growth conditions. In the prototypical two …