Exosomes are secreted small extracellular vesicles (EVs) packaged with diverse biological
cargo. They mediate complex intercellular communications among cells in maintenance of …

Inflammatory bowel disease (IBD), characterized primarily by gastrointestinal inflammation,
predominantly manifests as Crohn's disease (CD) and ulcerative colitis (UC). It is …

Background: Accumulating literature demonstrates that long noncoding RNAs (lncRNAs) are
involved in ferroptosis and gastric cancer progression. However, the predictive value of …

Patients with inflammatory bowel disease (IBD) have a high risk for colorectal cancer (CRC).
This cancer type, which is strongly associated with chronic inflammation, is called colitis …

Ferroptosis is a unique cell death modality triggered by iron-dependent lipid peroxidation,
with cysteine metabolism and glutathione-dependent antioxidant defence responses as the …

Background: Ferroptosis is a form of regulated cell death that occurs as a consequence of
lethal lipid peroxidation. A wealth of studies has demonstrated that ferroptosis profoundly …

多核型髓源抑制性细胞(PMN-MDSCs) 在肿瘤的免疫逃逸中扮演重要角色, 尤其体现在逃逸T
淋巴细胞免疫监视方面. 肿瘤干细胞具有病理性活化中性粒细胞(PMNs) 诱导PMN-MDSCs …

Endocrine therapies (eg tamoxifen and aromatase inhibitors) targeting estrogen action are
effective in decreasing mortality of breast cancer. However, their efficacy is limited by …

Periodontal diseases present a significant challenge to our healthcare system in terms of
morbidity from the disease itself as well as their putative and deleterious effects on systemic …

Although insulin-like growth factor-1 receptor (IGF-1R) has been accepted as a major
determinant of cancers, its biological roles and corresponding mechanisms in tumorigenesis …