Exosomes in cancer development
K Stefanius, K Servage, K Orth - Current opinion in genetics & development, 2021 - Elsevier
Exosomes are secreted small extracellular vesicles (EVs) packaged with diverse biological
cargo. They mediate complex intercellular communications among cells in maintenance of …
cargo. They mediate complex intercellular communications among cells in maintenance of …
[HTML][HTML] Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of …
H Zhang, Y Shi, C Lin, C He, S Wang, Q Li… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD), characterized primarily by gastrointestinal inflammation,
predominantly manifests as Crohn's disease (CD) and ulcerative colitis (UC). It is …
predominantly manifests as Crohn's disease (CD) and ulcerative colitis (UC). It is …
[HTML][HTML] A ferroptosis-related lncRNAs signature predicts prognosis and therapeutic response of gastric cancer
S Xiao, X Liu, L Yuan, F Wang - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Background: Accumulating literature demonstrates that long noncoding RNAs (lncRNAs) are
involved in ferroptosis and gastric cancer progression. However, the predictive value of …
involved in ferroptosis and gastric cancer progression. However, the predictive value of …
Molecular Pathogenesis of Colitis-associated Colorectal Cancer: Immunity, Genetics, and Intestinal Microecology
Y Yin, J Wan, J Yu, K Wu - Inflammatory Bowel Diseases, 2023 - academic.oup.com
Patients with inflammatory bowel disease (IBD) have a high risk for colorectal cancer (CRC).
This cancer type, which is strongly associated with chronic inflammation, is called colitis …
This cancer type, which is strongly associated with chronic inflammation, is called colitis …
[HTML][HTML] The putative role of ferroptosis in gastric cancer: a review
L Wang, H Wang - European Journal of Cancer Prevention, 2023 - journals.lww.com
Ferroptosis is a unique cell death modality triggered by iron-dependent lipid peroxidation,
with cysteine metabolism and glutathione-dependent antioxidant defence responses as the …
with cysteine metabolism and glutathione-dependent antioxidant defence responses as the …
[HTML][HTML] Expression of ferroptosis-related genes shapes tumor microenvironment and pharmacological profile in gastric cancer
S Xiao, X Liu, L Yuan, X Chen, F Wang - Frontiers in cell and …, 2021 - frontiersin.org
Background: Ferroptosis is a form of regulated cell death that occurs as a consequence of
lethal lipid peroxidation. A wealth of studies has demonstrated that ferroptosis profoundly …
lethal lipid peroxidation. A wealth of studies has demonstrated that ferroptosis profoundly …
基于肿瘤干细胞诱导多核型髓源抑制性细胞形成介导免疫逃逸探讨中医扶正解毒法防治肿瘤转移的可能机制
毛启远, 张英, 李道睿, 郑琦, 赵志正, 林洪生, 王学谦 - 北京中医药, 2023 - bjtcm.net
多核型髓源抑制性细胞(PMN-MDSCs) 在肿瘤的免疫逃逸中扮演重要角色, 尤其体现在逃逸T
淋巴细胞免疫监视方面. 肿瘤干细胞具有病理性活化中性粒细胞(PMNs) 诱导PMN-MDSCs …
淋巴细胞免疫监视方面. 肿瘤干细胞具有病理性活化中性粒细胞(PMNs) 诱导PMN-MDSCs …
S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation …
Q Wang, J Zheng, JX Zou, J Xu, F Han, S Xiang… - Chemico-Biological …, 2020 - Elsevier
Endocrine therapies (eg tamoxifen and aromatase inhibitors) targeting estrogen action are
effective in decreasing mortality of breast cancer. However, their efficacy is limited by …
effective in decreasing mortality of breast cancer. However, their efficacy is limited by …
Oral inflammatory load: Neutrophils as oral health biomarkers
W Khoury, J Glogauer, HC Tenenbaum… - Journal of Periodontal …, 2020 - Wiley Online Library
Periodontal diseases present a significant challenge to our healthcare system in terms of
morbidity from the disease itself as well as their putative and deleterious effects on systemic …
morbidity from the disease itself as well as their putative and deleterious effects on systemic …
Heterozygous knockout insulin-like growth factor-1 receptor (IGF-1R) regulates mitochondrial functions and prevents colitis and colorectal cancer
SQ Wang, XY Yang, SX Cui, XJ Qu - Free Radical Biology and Medicine, 2019 - Elsevier
Although insulin-like growth factor-1 receptor (IGF-1R) has been accepted as a major
determinant of cancers, its biological roles and corresponding mechanisms in tumorigenesis …
determinant of cancers, its biological roles and corresponding mechanisms in tumorigenesis …