Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis

S Zhang, Y Liu, Y Cao, S Zhang, J Sun… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

Poloxamer: A versatile tri-block copolymer for biomedical applications

P Zarrintaj, JD Ramsey, A Samadi, Z Atoufi, MK Yazdi… - Acta biomaterialia, 2020 - Elsevier
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases

W He, N Kapate, CW Shields IV, S Mitragotri - Advanced drug delivery …, 2020 - Elsevier
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Nanomedicines for cardiovascular disease

BR Smith, ER Edelman - Nature Cardiovascular Research, 2023 - nature.com
The leading cause of death in the world, cardiovascular disease (CVD), remains a
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …

[HTML][HTML] Molecularly targeted nanomedicine enabled by inorganic nanoparticles for atherosclerosis diagnosis and treatment

X Zhang, F Centurion, A Misra, S Patel, Z Gu - Advanced drug delivery …, 2023 - Elsevier
Atherosclerosis, a chronic cardiovascular disease caused by plaque development in
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …

Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

Site‐specific microRNA‐33 antagonism by pH‐responsive nanotherapies for treatment of atherosclerosis via regulating cholesterol efflux and adaptive immunity

C Li, Y Dou, Y Chen, Y Qi, L Li, S Han… - Advanced functional …, 2020 - Wiley Online Library
Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular
diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse …

Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/-mice

M Kim, A Sahu, Y Hwang, GB Kim, GH Nam, IS Kim… - Biomaterials, 2020 - Elsevier
Unresolved inflammation is a hallmark of many deadly diseases including atherosclerosis, a
silent pathological condition behind majority of cardiovascular diseases. Yet, anti …

Current advances in the diagnostic imaging of atherosclerosis: insights into the pathophysiology of vulnerable plaque

NV Mushenkova, VI Summerhill, D Zhang… - International journal of …, 2020 - mdpi.com
Atherosclerosis is a lipoprotein-driven inflammatory disorder leading to a plaque formation
at specific sites of the arterial tree. After decades of slow progression, atherosclerotic plaque …

Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics

C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …