[图书][B] Nucleic acids in chemistry and biology

GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Reversibly photoswitchable nucleosides: synthesis and photochromic properties of diarylethene-functionalized 7-deazaadenosine derivatives

M Singer, A Jäschke - Journal of the American Chemical Society, 2010 - ACS Publications
Photochromic nucleosides were designed that combine the structural features and
molecular recognition properties of nucleic acids with the light-sensitivity of diarylethenes …

Progress in 7-deazapurine-pyrrolo [2, 3-d] pyrimidine-ribonucleoside synthesis

F Seela, X Peng - Current Topics in Medicinal Chemistry, 2006 - ingentaconnect.com
This review reports on the synthesis of 7-deazapurine ribonucleosides, including C-
nucleosides, 2'-C-methyl derivatives and L-enantiomers. It covers the various aspects of …

A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2′-deoxy-β-ribonucleosides

F Yang, Y Zhu, B Yu - Chemical Communications, 2012 - pubs.rsc.org
A dramatic concentration effect on the stereoselectivity of N-glycosylation, which is
attributable to a low-concentration-facilitated remote-participation, has been disclosed …

7-Functionalized 7-deazapurine β-d and β-l-ribonucleosides related to tubercidin and 7-deazainosine: glycosylation of pyrrolo [2, 3-d] pyrimidines with 1-O-acetyl-2, 3 …

F Seela, X Ming - Tetrahedron, 2007 - Elsevier
Several 7-functionalized 7-deazapurine ribonucleosides were prepared. Glycosylation of 7-
halogenated 6-chloro-7-deazapurines with 1-O-acetyl-2, 3, 5-tri-O-benzoyl-β-d-ribofuranose …

Generation of DNA interstrand cross-links by post-synthetic reductive amination

T Angelov, A Guainazzi, OD Schärer - Organic letters, 2009 - ACS Publications
DNA interstrand cross-links (ICLs) are the clinically most relevant adducts formed by many
antitumor agents. To facilitate the study of biological responses triggered by ICLs, we …

Inhibition of human telomerase by 7-deaza-2′-deoxyguanosine nucleoside triphosphate analogs: potent inhibition by 6-thio-7-deaza-2′-deoxyguanosine 5 …

TM Fletcher, BE Cathers, KS Ravikumar, BM Mamiya… - Bioorganic …, 2001 - Elsevier
We have examined analogs of the previously reported 7-deaza-2′-deoxypurine nucleoside
triphosphate series of human telomerase inhibitors. Two new telomerase-inhibiting …

[PDF][PDF] Substituted benzimidazoles: antiviral activity and synthesis of nucleosides.

S Budow, M Kozlowska, A Gorska… - … : Online Journal of …, 2009 - arkat-usa.org
The antiviral activity of a series of benzimidazole derivatives and substituted benzimidazole
β-L-and β-D-2'-deoxyribonucleosides against selected RNA and DNA viruses including HIV …

Alternating d(GC)3 and d(CG)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza-2'-deoxyguanosine in place of dG

F Seela, H Driller - Nucleic acids research, 1989 - academic.oup.com
The synthesis of alternating hexamers (8–13) derived from d (CG) 3 or d (GC) 3 but
containing c7z8Gd (2) or c7Gd [3) instead of dG is described employing phosphoramidite …

8‐Aza‐7‐deazaadenine N8‐ and N8‐(β‐D‐2′‐Deoxyribofuranosides): Building blocks for automated DNA synthesis and properties of oligodeoxyribonucleotides

F Seela, K Kaiser - Helvetica chimica acta, 1988 - Wiley Online Library
Abstract Oligonucleotides with alternating 8‐aza‐7‐deaza‐2′‐deoxyadenosine (=
c7z8Ad2) and dT residues (see 11, 14 and 16) or 4‐aminopyrazolo [3, 4‐d] pyrimidine N2 …