Fewer than one in 20 adult patients with cancer enroll in cancer clinical trials. Although
barriers to trial participation have been the subject of frequent study, the rate of trial …

Objective To estimate the proportion of participants in clinical trials who understand different
components of informed consent. Methods Relevant studies were identified by a systematic …

Purpose: Although patients with cancer overwhelming prefer oral to intravenous
chemotherapy, little is known about adherence to oral agents. We aimed to identify the rates …

Background Informed consent is a critical component of clinical research. Different methods
of presenting information to potential participants of clinical trials may improve the informed …

Objective Some researchers claim that the quality of informed consent of clinical research
participants in developing countries is worse than in developed countries. To evaluate this …

Background The process of informed consent for enrolment to a clinical research study can
be complex for both participants and research staff. Challenges include respecting the …

Randomised controlled trials (RCTs) represent the gold standard methodology for
determining effectiveness of healthcare interventions. Poor recruitment to RCTs can threaten …

OBJECTIVE: To understand the psychosocial outcomes related to decision-making
processes of individuals eligible for participation in clinical trials. METHODS: Individuals …

OBJECTIVE: To investigate the barriers, modifiers, and benefits involved in participating in
randomized controlled trials of cancer therapies as perceived by health care providers and …

Background: Barriers to randomised clinical trial (RCT) recruitment include failure to identify
eligible patients, reluctance of staff to approach them and attitudes of some health-care …