This is a narrative review on the role of biomarkers in the diagnosis of neonatal sepsis. We
describe the difficulties to obtain standardized definitions in neonatal sepsis and discuss the …

Neonatal sepsis continues to be a common and significant health care burden, especially in
very-low-birth-weight infants (VLBW< 1500 g). Though intrapartum antibiotic prophylaxis has …

Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Rationale: Although the outcome of sepsis benefits from the prompt administration of
appropriate antibiotics on correct diagnosis, the assessment of infection in critically ill …

As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Sepsis is a clinical syndrome defined by physiologic changes indicative of systemic
inflammation, which are likely attributable to documented or suspected infection. Septic …

Sepsis is the most frequent cause of death in non-coronary intensive care units (ICUs). In the
past 10 years, progress has been made in the early identification of septic patients and in …

Identifying neonates with sepsis is complicated by variability in clinical presentation. The
incidence of early onset sepsis (EOS) resulting from invasive group B streptococcal (GBS) …

Neutrophilic granulocytes express Fcγ receptor (FcγR)[cluster of differentiation 64 (CD64)
antigen] only when they are activated. Neutrophil CD64, demonstrated using flow cytometry …

OBJECTIVE: We performed a systematic review and meta-analysis of studies to evaluate the
diagnostic accuracy of expression of CD64 on polymorphonuclear neutrophils (PMN) as a …