The urokinase receptor: a multifunctional receptor in cancer cell biology. therapeutic implications

A Li Santi, F Napolitano, N Montuori… - International journal of …, 2021 - mdpi.com
Proteolysis is a key event in several biological processes; proteolysis must be tightly
controlled because its improper activation leads to dramatic consequences. Deregulation of …

[HTML][HTML] The urokinase receptor: a multifunctional receptor in Cancer Cell Biology. Therapeutic implications

AL Santi, F Napolitano, N Montuori… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Proteolysis is a key event in several biological processes; proteolysis must be tightly
controlled because its improper activation leads to dramatic consequences. Deregulation of …

The diagnostic and prognostic value of suPAR in patients with sepsis: a systematic review and meta-analysis

Q Huang, H Xiong, P Yan, T Shuai, J Liu, L Zhu, J Lu… - Shock, 2020 - journals.lww.com
Background: Soluble urokinase-type plasminogen activator receptor (suPAR) has the
potential to diagnose infectious diseases. Due to the lack of reliable biomarkers and the …

Neutrophils are a main source of circulating suPAR predicting outcome in critical illness

H Gussen, P Hohlstein, M Bartneck, KT Warzecha… - Journal of intensive …, 2019 - Springer
Background Circulating levels of soluble urokinase plasminogen activation receptor
(suPAR) have been proposed as a prognostic biomarker in patients with critical illness and …

Serum soluble urokinase-type plasminogen activator receptor as a biological marker of bacterial infection in adults: a systematic review and meta-analysis

W Ni, Y Han, J Zhao, J Cui, K Wang, R Wang, Y Liu - Scientific reports, 2016 - nature.com
The serum concentration of soluble urokinase-type plasminogen activator receptor (suPAR)
reflects immune activation. We performed a meta-analysis to evaluate the usefulness of …

Value of lipopolysaccharide binding protein as diagnostic marker of infection in adult cancer patients with febrile neutropenia: comparison with C-reactive protein …

L García de Guadiana-Romualdo… - Supportive Care in …, 2015 - Springer
Purpose Early detection of infection is essential for initial management of cancer patients
with chemotherapy-associated febrile neutropenia in the emergency department. In this …

Oncologic emergencies: the fever with too few neutrophils

B Long, A Koyfman - The Journal of Emergency Medicine, 2019 - Elsevier
Background Cancer is associated with a variety of complications, including neutropenic
fever, which can result in severe morbidity and mortality. This oncologic emergency requires …

Soluble urokinase-type plasminogen activator receptor (suPAR)–a possible biomarker for bacteremia in sepsis/Forma solubilă a receptorului pentru activatorul de …

AM Georgescu, J Szederjesi, S Voidăzan… - Revista Romana De …, 2015 - sciendo.com
Background. Validating new sepsis biomarkers can contribute to early diagnosis and
initiation of therapy. The aim of this study is to evaluate the sepsis predictive capacity of …

Soluble urokinase‑type plasminogen activator receptor and urokinase‑type plasminogen activator receptor contribute to chemoresistance in leukemia

H Guo, LX Zhou, H Ma, B Liu, J Cheng… - Oncology …, 2017 - spandidos-publications.com
The soluble urokinase-type plasminogen activator receptor (suPAR) and the urokinase‑type
plasminogen activator receptor (uPAR) have been proposed as useful biomarkers of tumor …

Comparison of soluble urokinase plasminogen activator receptor, soluble triggering receptor expressed on myeloid cells 1, procalcitonin and C-reactive protein in …

Y Xiao, H Luo, B Zhou, X Dai, J Huang, L Duan… - Rheumatology …, 2017 - Springer
The aim of the study was to measure the diagnostic values of biomarkers of bacterial
infection in idiopathic inflammatory myopathy (IIM) patients. The serum and clinical data of …