Next-generation sequencing (NGS) in COVID-19: a tool for SARS-CoV-2 diagnosis, monitoring new strains and phylodynamic modeling in molecular epidemiology

G John, NS Sahajpal, AK Mondal, S Ananth… - Current issues in …, 2021 - mdpi.com
This review discusses the current testing methodologies for COVID-19 diagnosis and
explores next-generation sequencing (NGS) technology for the detection of SARS-CoV-2 …

Reviving the transcriptome studies: an insight into the emergence of single-molecule transcriptome sequencing

B Wang, V Kumar, A Olson, D Ware - Frontiers in genetics, 2019 - frontiersin.org
Advances in transcriptomics have provided an exceptional opportunity to study functional
implications of the genetic variability. Technologies such as RNA-Seq have emerged as …

[HTML][HTML] Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

A Bagaev, N Kotlov, K Nomie, V Svekolkin, A Gafurov… - Cancer cell, 2021 - cell.com
The clinical use of molecular targeted therapy is rapidly evolving but has primarily focused
on genomic alterations. Transcriptomic analysis offers an opportunity to dissect the …

Computational methods for chromosome-scale haplotype reconstruction

S Garg - Genome biology, 2021 - Springer
High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid
genomes, and metagenomes provide important insights into genetic variation associated …

The emerging roles of NGS in clinical oncology and personalized medicine

BM Hussen, ST Abdullah, A Salihi, DK Sabir… - … -Research and Practice, 2022 - Elsevier
Next-generation sequencing (NGS) has been increasingly popular in genomics studies over
the last decade, as new sequencing technology has been created and improved. Recently …

[HTML][HTML] Medical disease analysis using neuro-fuzzy with feature extraction model for classification

H Das, B Naik, HS Behera - Informatics in Medicine Unlocked, 2020 - Elsevier
Medical disease classification using machine learning algorithms is a challenging task due
to the nature of data, which can contain incomplete, uncertain, and imprecise information …

The liquid biopsy in the management of colorectal cancer: an overview

M Vacante, R Ciuni, F Basile, A Biondi - Biomedicines, 2020 - mdpi.com
Currently, there is a crucial need for novel diagnostic and prognostic biomarkers with high
specificity and sensitivity in patients with colorectal cancer. A “liquid biopsy” is characterized …

Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics

S Mukherjee, S Perveen, A Negi, R Sharma - Tuberculosis, 2023 - Elsevier
Tuberculosis has remained a global concern for public health affecting the lives of people for
ages. Approximately 10 million people are affected by the disease and 1.5 million succumb …

Exploration of probiotic microbial biodiversity in acidic environments (curd) and their futuristic pharmaceutical applications

P Biswal, S Ghosh, A Pal, AP Das - Geomicrobiology journal, 2022 - Taylor & Francis
Probiotics are potential health-promoting microorganisms representing a significant health
aid with diverse pharmaceutical applications. But its role in modulating the human gut …

A 16S next generation sequencing based molecular and bioinformatics pipeline to identify processed meat products contamination and mislabelling

NS Chaora, KS Khanyile, K Magwedere, R Pierneef… - Animals, 2022 - mdpi.com
Simple Summary Meat adulteration and fraud encompasses the deliberate fraudulent
addition or substitution of proteins of animal or plant origin in edible products primarily for …