Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward

AK Nanayakkara, HW Boucher… - CA: a cancer journal …, 2021 - Wiley Online Library
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

The challenge of antimicrobial resistance: what economics can contribute

LSJ Roope, RD Smith, KB Pouwels, J Buchanan… - Science, 2019 - science.org
BACKGROUND Antimicrobial resistance (AMR) is increasing, driven by widespread
antibiotic use. The wide availability of effective antibiotics is under threat, jeopardizing …

Recovery of gut microbiota of healthy adults following antibiotic exposure

A Palleja, KH Mikkelsen, SK Forslund, A Kashani… - Nature …, 2018 - nature.com
To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics
resistance genes, collectively called their resistome. Using shotgun sequencing-based …

Reducing antimicrobial use in food animals

TP Van Boeckel, EE Glennon, D Chen, M Gilbert… - Science, 2017 - science.org
The large and expanding use of antimicrobials in livestock, a consequence of growing
global demand for animal protein, is of considerable concern in light of the threat of …

The Lancet Infectious Diseases Commission on antimicrobial resistance: 6 years later

R Laxminarayan, T Van Boeckel, I Frost… - The Lancet Infectious …, 2020 - thelancet.com
Summary In 2013, a Lancet Infectious Diseases Commission described the state of
antimicrobial resistance worldwide. Since then, greater awareness of the public health …

Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem

C Llor, L Bjerrum - Therapeutic advances in drug safety, 2014 - journals.sagepub.com
Antimicrobial resistance is a global public health challenge, which has accelerated by the
overuse of antibiotics worldwide. Increased antimicrobial resistance is the cause of severe …

Antibiotics in agriculture and the risk to human health: how worried should we be?

Q Chang, W Wang, G Regev‐Yochay… - Evolutionary …, 2015 - Wiley Online Library
The use of antibiotics in agriculture is routinely described as a major contributor to the
clinical problem of resistant disease in human medicine. While a link is plausible, there are …

Resistencia bacteriana a los antibióticos: una crisis global

JI Alós - Enfermedades infecciosas y microbiología clínica, 2015 - Elsevier
La introducción de los antibióticos en la práctica clínica supuso una de las intervenciones
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …

The ecology of extended-spectrum β-lactamases (ESBLs) in the developed world

Y Doi, A Iovleva, RA Bonomo - Journal of travel medicine, 2017 - academic.oup.com
Background: Since the initial appearance in the 1980s, Enterobacteriaceae producing
extended-spectrum β-lactamase (ESBL) have increased in prevalence and emerged as a …

Overview: global and local impact of antibiotic resistance

RR Watkins, RA Bonomo - Infectious Disease Clinics, 2016 - id.theclinics.com
The discovery and clinical implementation of antibiotics is one of the greatest achievements
in the history of medicine. These miracle drugs treat infections ranging from minor to life …