[HTML][HTML] Mechanistic insight and clinical implications of ischemia/reperfusion injury post liver transplantation

J Liu, K Man - Cellular and molecular gastroenterology and …, 2023 - Elsevier
Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead
to a high incidence of early allograft dysfunction and graft failure. The mechanism of hepatic …

Hippo pathway in cell–cell communication: emerging roles in development and regeneration

A Nita, T Moroishi - Inflammation and Regeneration, 2024 - Springer
The Hippo pathway is a central regulator of tissue growth that has been widely studied in
mammalian organ development, regeneration, and cancer biology. Although previous …

[HTML][HTML] Updates on the immune cell basis of hepatic ischemia-reperfusion injury

MJ Heo, JH Suh, KL Poulsen, C Ju, KH Kim - Molecules and Cells, 2023 - Elsevier
Liver ischemia-reperfusion injury (IRI) is the main cause of organ dysfunction and failure
after liver surgeries including organ transplantation. The mechanism of liver IRI is complex …

Inhibition of macrophage migration inhibitory factor (MIF) suppresses apoptosis signal-regulating kinase 1 to protect against liver ischemia/reperfusion injury

S Chen, Q Yu, Y Song, Z Cui, M Li, C Mei… - Frontiers in …, 2022 - frontiersin.org
Background: Hepatic ischemia–reperfusion (I/R) injury is a major complication leading to
surgical failures in liver resection, transplantation, and hemorrhagic shock. The role of …

Extracellular vesicles as potential biomarkers and treatment options for liver failure: A systematic review up to March 2022

W Lu, H Tang, S Li, L Bai, Y Chen - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Extracellular vesicles (EVs) carrying functional cargoes are emerging as
biomarkers and treatment strategies in multiple liver diseases. Nevertheless, the potential of …

Hepatoprotective Role of 4‐Octyl Itaconate in Concanavalin A‐Induced Autoimmune Hepatitis

W Yang, Y Wang, P Zhang, T Wang, C Li… - Mediators of …, 2022 - Wiley Online Library
4‐Octyl itaconate (OI) is a novel anti‐inflammatory metabolite that exerts protective effects in
many various disease models. However, its function in autoimmune hepatitis‐(AIH‐) …

[PDF][PDF] Hippo-Yap 信号通路在肝脏疾病中的作用及其研究进展

欧可, 彭秀达, 费书珂 - 中国普通外科杂志, 2023 - zpwz.net
摘要河马(Hippo) 信号通路最初作为一种抑制果蝇组织生长的通路被发现, 主要由MST1/2,
LATS1/2 和Yap/TAZ 三种激酶级联组成. 随着研究的进展, 在哺乳动物中Hippo …

Sanyang Chen1, 2, 3†, Qiwen Yu3, 4†, Yaodong Song1, 2, Zongchao Cui1, 2, Mengke Li1, 2, Chaopeng Mei1, 2, Huning Cui1, 2, Shengli Cao3, 4* and Changju …

S Cao, C Zhu, S Chen, Q Yu, Y Song… - … , novel targets and …, 2023 - books.google.com
Background: Hepatic ischemia–reperfusion (I/R) injury is a major complication leading to
surgical failures in liver resection, transplantation, and hemorrhagic shock. The role of …

Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity …

P Carrillo-Rodríguez, JÁ Robles-Guirado… - Frontiers in …, 2022 - frontiersin.org
In CD38-deficient (Cd38-/-) mice intraperitoneal injection of pristane induces a lupus-like
disease, which is milder than that induced in WT mice, showing significant differences in the …