The actin cytoskeleton orchestrates cell mechanics and facilitates the physical integration of
cells into tissues, while tissue‐scale forces and extracellular rigidity in turn govern cell …

The motor protein myosin-15 is necessary for the development and maintenance of
mechanosensory stereocilia, and mutations in myosin-15 cause hereditary deafness. In …

Microtubules are central elements of the eukaryotic cytoskeleton that often function as part of
branched networks. Current models for branching include nucleation of new microtubules …

Uptake of large volumes of extracellular fluid by actin-dependent macropinocytosis has an
important role in infection, immunity and cancer development. A key question is how actin …

A number of key cell processes rely on specific assemblies of actin filaments, which are all
constructed from nearly identical building blocks: the abundant and extremely conserved …

Background In the last three decades, the Baculovirus expression vector system (BEV) has
evolved to one of the most widely used eukaryotic systems for heterologous protein …

Actin binding compounds are widely used tools in cell biology. We compare the biological
and biochemical effects of miuraenamide A and jasplakinolide, a structurally related …

Cell migration is driven by propulsive forces derived from polymerizing actin that pushes and
extends the plasma membrane. The underlying actin network is constantly undergoing …

Within a shared cytoplasm, filamentous actin (F-actin) plays numerous and critical roles
across the cell body. Cells rely on actin-binding proteins (ABPs) to organize F-actin and to …

The regulation of actin dynamics is essential for various cellular processes. Former evidence
suggests a correlation between the function of non-conventional myosin motors and actin …