Background There has been increased interest in the role of cannabis for treating medical
conditions. The availability of different cannabis-based products can make the side effects of …

The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …

Background Intracranial-pressure monitoring is considered the standard of care for severe
traumatic brain injury and is used frequently, but the efficacy of treatment based on …

Background Although cannabis and cannabinoids are widely used with therapeutic
purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis …

The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of
physiological processes and unsurprisingly possesses considerable potential targets for the …

Understanding tissue alterations at an early stage following traumatic brain injury (TBI) is
critical for injury management and limiting severe consequences from secondary injury. We …

Background Traumatic brain injury (TBI) is a major public health problem and a fundamental
cause of morbidity and mortality worldwide. The burden of TBI disproportionately affects low …

Increased intracranial pressure (ICP) can be a medical or surgical emergency. 1 Both
intracranial and systemic events contribute to increased ICP after traumatic brain injury (TBI) …

We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in
mice. As true for individuals that have experienced mild TBI, mice subjected to 50–60 psi …

We have previously reported that mild TBI created by focal left-side cranial blast in mice
produces widespread axonal injury, microglial activation, and a variety of functional deficits …