Latest advances in cryogel technology for biomedical applications

A Memic, T Colombani, LJ Eggermont… - Advanced …, 2019 - Wiley Online Library
There exists a technological need for advanced materials with improved properties for
emerging biomedical applications. Recent developments in macroporous materials have …

[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

F Hashemi-Afzal, H Fallahi, F Bagheri, MN Collins… - Bioactive Materials, 2025 - Elsevier
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

Cryogel/hydrogel biomaterials and acupuncture combined to promote diabetic skin wound healing through immunomodulation

TY Chen, TK Wen, NT Dai, S Hsu - Biomaterials, 2021 - Elsevier
Unhealed chronic wounds often deteriorate into multiple infection with several kinds of
bacteria and excessive proteolytic wound exudate and remains one of the common …

Adipose stem cell translational applications: from bench-to-bedside

C Argentati, F Morena, M Bazzucchi… - International journal of …, 2018 - mdpi.com
During the last five years, there has been a significantly increasing interest in adult adipose
stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant …

The application of bioreactors for cartilage tissue engineering: advances, limitations, and future perspectives

L Fu, P Li, H Li, C Gao, Z Yang, T Zhao… - Stem cells …, 2021 - Wiley Online Library
Tissue engineering (TE) has brought new hope for articular cartilage regeneration, as TE
can provide structural and functional substitutes for native tissues. The basic elements of TE …

miR-381-abundant small extracellular vesicles derived from kartogenin-preconditioned mesenchymal stem cells promote chondrogenesis of MSCs by targeting …

H Jing, X Zhang, K Luo, Q Luo, M Yin, W Wang, Z Zhu… - Biomaterials, 2020 - Elsevier
Small extracellular vesicles (sEVs) derived from mesenchymal stem cells have been shown
to possess potent regenerative potential. In this study, we evaluated the chondrogenic effect …

Physically active bioreactors for tissue engineering applications

N Castro, S Ribeiro, MM Fernandes… - Advanced …, 2020 - Wiley Online Library
Tissue engineering (TE) is a strongly expanding research area. TE approaches require
biocompatible scaffolds, cells, and different applied stimuli, which altogether mimic the …

Osteochondral injury, management and tissue engineering approaches

G Jacob, K Shimomura, N Nakamura - Frontiers in Cell and …, 2020 - frontiersin.org
Osteochondral lesions (OL) are a common clinical problem for orthopedic surgeons
worldwide and are associated with multiple clinical scenarios ranging from trauma to …

A roadmap of in vitro models in osteoarthritis: a focus on their biological relevance in regenerative medicine

I Bartolotti, L Roseti, M Petretta, B Grigolo… - Journal of clinical …, 2021 - mdpi.com
Osteoarthritis (OA) is a multifaceted musculoskeletal disorder, with a high prevalence
worldwide. Articular cartilage and synovial membrane are among the main biological targets …

Glycosaminoglycan-based cryogels as scaffolds for cell cultivation and tissue regeneration

A Wartenberg, J Weisser, M Schnabelrauch - Molecules, 2021 - mdpi.com
Cryogels are a class of macroporous, interconnective hydrogels polymerized at sub-zero
temperatures forming mechanically robust, elastic networks. In this review, latest advances …