[HTML][HTML] Exosome-based immunotherapy: a promising approach for cancer treatment

Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …

[HTML][HTML] Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications

A Hazrati, S Soudi, K Malekpour, M Mahmoudi… - Biomarker …, 2022 - Springer
Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …

[HTML][HTML] Exosomes: A potential tool for immunotherapy of ovarian cancer

X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …

Exosomes as biomarkers and therapeutic delivery for autoimmune diseases: opportunities and challenges

Y Fang, J Ni, YS Wang, Y Zhao, LQ Jiang, C Chen… - Autoimmunity …, 2023 - Elsevier
Exosomes are spherical lipid bilayer vesicles composed of lipids, proteins and nucleic acids
that deliver signaling molecules through a vesicular transport system to regulate the function …

[HTML][HTML] NK cells are never alone: crosstalk and communication in tumour microenvironments

Y Zhou, L Cheng, L Liu, X Li - Molecular Cancer, 2023 - Springer
Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

[HTML][HTML] Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …

[HTML][HTML] NK cell-based tumor immunotherapy

H Zhang, L Yang, T Wang, Z Li - Bioactive materials, 2024 - Elsevier
Natural killer (NK) cells display a unique inherent ability to identify and eliminate virus-
infected cells and tumor cells. They are particularly powerful for elimination of hematological …

Conscription of immune cells by light‐activatable silencing NK‐derived exosome (LASNEO) for synergetic tumor eradication

M Zhang, W Shao, T Yang, H Liu, S Guo… - Advanced …, 2022 - Wiley Online Library
Exosomes derived from natural killer (NK) cells (NEO) constitute promising antineoplastic
nano‐biologics because of their versatile functions in immune regulation. However, a …

Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …

[HTML][HTML] Exosome regulation of immune response mechanism: Pros and cons in immunotherapy

JM Essola, M Zhang, H Yang, F Li, B Xia… - Bioactive Materials, 2024 - Elsevier
Due to its multiple features, including the ability to orchestrate remote communication
between different tissues, the exosomes are the extracellular vesicles arousing the highest …