Human immunodeficiency viruses in the developing world

M Essex - Advances in virus research, 1999 - Elsevier
Publisher Summary This chapter focuses on the effects of human immunodeficiency viruses
in the developing world. Acquired immunodeficiency syndrome (AIDS) has become a major …

Natural protection against HIV-1 infection provided by HIV-2

K Travers, S Mboup, R Marlink, A Guèye-Nidaye… - Science, 1995 - science.org
Significant differences have been observed in the rates of transmission and disease
development in human immunodeficiency virus (HIV) types 1 and 2. Because many HIV-2 …

Twenty years of prospective molecular epidemiology in Senegal: changes in HIV diversity

DJ Hamel, JL Sankalé, G Eisen, ST Meloni… - AIDS research and …, 2007 - liebertpub.com
Over a 20-year period we have observed the dynamics of HIV-1 subtypes and HIV-2
infection in a prospective cohort of registered female sex workers (FSW) in Dakar, Senegal …

Highly active antiretroviral therapy and viral response in HIV type 2 infection

C Mullins, G Eisen, S Popper, AD Sarr… - Clinical infectious …, 2004 - academic.oup.com
Human immunodeficiency virus type 2 (HIV-2), the second human retrovirus known to cause
AIDS, is endemic to West Africa but is infrequently found outside this region. We present a …

In vitro correlates of HIV-2-mediated HIV-1 protection

EG Kokkotou, JL Sankalé, I Mani… - Proceedings of the …, 2000 - National Acad Sciences
A prospective study of high-risk commercial sex workers in Senegal has shown that HIV-2
infection may reduce the risk of subsequent HIV-1 infection; these findings have been …

HIV-1 and HIV-2 dual infection: lack of HIV-2 provirus correlates with low CD4+ lymphocyte counts

AD Sarr, DJ Hamel, I Thior, E Kokkotou, JL Sankalé… - Aids, 1998 - journals.lww.com
Objective: We conducted this study to genetically characterize dual infection in individuals
demonstrating a dual serological profile. Methods: All subjects were first evaluated by …

Viral dynamics of primary HIV-1 infection in Senegal, West Africa

AD Sarr, G Eisen, A Guèye-Ndiaye… - The Journal of …, 2005 - academic.oup.com
Background Few studies have addressed primary human immunodeficiency virus (HIV) type
1 infection in sub-Saharan Africa, where the epidemic is of a predominantly heterosexual …

Human Immunodeficiency Virus Type 2 (HIV-2) Biology and Pathogenesis

PJ Kanki - AIDS in Asia, 1999 - Springer
Human immunodeficiency virus type 2 (HIV-2) is the second human immunodeficiency virus
in the class of human retro-viruses; it constitutes the closest known virus related to the …

Field evaluation of a combination of monospecific enzyme-linked immunosorbent assays for type-specific diagnosis of human immunodeficiency virus type 1 (HIV-1) …

JN Nkengasong, C Maurice, S Koblavi… - Journal of clinical …, 1998 - Am Soc Microbiol
Serologic distinction between human immunodeficiency virus type 1 (HIV-1) and HIV-2
infection is made difficult because of the cross-reactivity and high cost of existing …

Interaction with human immunodeficiency virus (HIV) type 2 predicts HIV type 1 genotype

AD Sarr, JL Sankalé, DJ Hamel, KU Travers… - Virology, 2000 - Elsevier
In West Africa, India, and certain regions of Europe, both human immunodeficiency viruses
types 1 and 2 (HIV-1 and HIV-2) are known to cocirculate. To investigate the HIV-1 subtypes …