The oral microbiota: dynamic communities and host interactions
RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
Oral biofilms: pathogens, matrix, and polymicrobial interactions in microenvironments
Biofilms are microbial communities embedded within an extracellular matrix, forming a
highly organized structure that causes many human infections. Dental caries (tooth decay) is …
highly organized structure that causes many human infections. Dental caries (tooth decay) is …
The structure of dental plaque microbial communities in the transition from health to dental caries and periodontal disease
AM Valm - Journal of molecular biology, 2019 - Elsevier
The human oral cavity harbors diverse communities of microbes that live as biofilms: highly
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …
Early childhood caries: epidemiology, aetiology, and prevention
F Meyer, J Enax - International journal of dentistry, 2018 - Wiley Online Library
Early childhood caries (ECC) is one of the most prevalent diseases in children worldwide.
ECC is driven by a dysbiotic state of oral microorganisms mainly caused by a sugar‐rich …
ECC is driven by a dysbiotic state of oral microorganisms mainly caused by a sugar‐rich …
Spatial mapping of polymicrobial communities reveals a precise biogeography associated with human dental caries
Tooth decay (dental caries) is a widespread human disease caused by microbial biofilms.
Streptococcus mutans, a biofilm-former, has been consistently associated with severe …
Streptococcus mutans, a biofilm-former, has been consistently associated with severe …
Candida albicans and Early Childhood Caries: A Systematic Review and Meta-Analysis
Oral Candida albicans has been detected in children with early childhood caries (ECC) and
has demonstrated cariogenic traits in animal models of the disease. Conversely, other …
has demonstrated cariogenic traits in animal models of the disease. Conversely, other …
Ferumoxytol nanoparticles target biofilms causing tooth decay in the human mouth
Severe tooth decay has been associated with iron deficiency anemia that disproportionally
burdens susceptible populations. Current modalities are insufficient in severe cases where …
burdens susceptible populations. Current modalities are insufficient in severe cases where …
Candida albicans stimulates Streptococcus mutans microcolony development via cross-kingdom biofilm-derived metabolites
Candida albicans is frequently detected with heavy infection of Streptococcus mutans in
plaque-biofilms from children affected with early-childhood caries, a prevalent and costly …
plaque-biofilms from children affected with early-childhood caries, a prevalent and costly …
Interkingdom assemblages in human saliva display group-level surface mobility and disease-promoting emergent functions
Fungi and bacteria often engage in complex interactions, such as the formation of
multicellular biofilms within the human body. Knowledge about how interkingdom biofilms …
multicellular biofilms within the human body. Knowledge about how interkingdom biofilms …
Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity
Ferumoxytol is a nanoparticle formulation approved by the US Food and Drug
Administration for systemic use to treat iron deficiency. Here, we show that, in addition …
Administration for systemic use to treat iron deficiency. Here, we show that, in addition …