Extracellular vesicle (EV) secretion is a highly conserved evolutionary trait in all organisms
in the three domains of life. The packaging and release of EVs appears to be a bulk-flow …

Pathway analysis, also known as gene-set enrichment analysis, is a multilocus analytic
strategy that integrates a priori, biological knowledge into the statistical analysis of high …

Background Gut microbiome and inflammatory bowel disease (IBD) are implicated in the
development of depression, but the effect of their interactions on the risk of depression …

Among the myriad of statistical methods that identify gene–gene interactions in the realm of
qualitative genome-wide association studies, gene-based interactions are not only powerful …

DNA sequence with a known physical position on a chromosome is called a genetic marker,
so the causal gene may identify with genetic markers in different kinds of hereditary …

Background Identifying gene interactions is a topic of great importance in genomics, and
approaches based on network models provide a powerful tool for studying these. Assuming …

Cardiometabolic diseases (CMDs) are complex disorders with a heterogenous phenotype,
which are caused by multiple factors including genetic factors. Single nucleotide …

ABSTRACT DNA sequence with a known physical position on a chromosome is called a
genetic marker, so the causal gene may identify with genetic markers in different kinds of …