Respiratory syncytial virus disease burden in adults aged 60 years and older in high‐income countries: A systematic literature review and meta‐analysis

M Savic, Y Penders, T Shi, A Branche… - Influenza and other …, 2023 - Wiley Online Library
Background Respiratory syncytial virus (RSV)‐associated acute respiratory infection (ARI) is
an underrecognized cause of illness in older adults. We conducted a systematic literature …

Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

[HTML][HTML] Respiratory syncytial virus prefusion F protein vaccine in older adults

A Papi, MG Ison, JM Langley, DG Lee… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults …

[HTML][HTML] Durability of neutralizing RSV antibodies following nirsevimab administration and elicitation of the natural immune response to RSV infection in infants

D Wilkins, Y Yuan, Y Chang, AA Aksyuk, BS Núñez… - Nature Medicine, 2023 - nature.com
Nirsevimab is an extended half-life monoclonal antibody specific for the prefusion
conformation of the respiratory syncytial virus (RSV) F protein, which has been studied in …

[HTML][HTML] Vaccine efficacy in adults in a respiratory syncytial virus challenge study

B Schmoele-Thoma, AM Zareba, Q Jiang… - … England Journal of …, 2022 - Mass Medical Soc
Background Although human respiratory syncytial virus (RSV) is an important cause of
illness and death in older adults, no RSV vaccine has been licensed. Methods In a phase 2a …

[HTML][HTML] Etiological and epidemiological features of acute respiratory infections in China

ZJ Li, HY Zhang, LL Ren, QB Lu, X Ren… - Nature …, 2021 - nature.com
Nationwide prospective surveillance of all-age patients with acute respiratory infections was
conducted in China between 2009‒2019. Here we report the etiological and …

Melatonin potentials against viral infections including COVID-19: Current evidence and new findings

KB Juybari, MH Pourhanifeh, A Hosseinzadeh… - Virus research, 2020 - Elsevier
Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

Safety and immunogenicity of a respiratory syncytial virus prefusion F (RSVPreF3) candidate vaccine in older adults: phase 1/2 randomized clinical trial

I Leroux-Roels, MG Davis, K Steenackers… - The Journal of …, 2023 - academic.oup.com
Background The aim of this study was to investigate safety and immunogenicity of vaccine
formulations against respiratory syncytial virus (RSV) containing the stabilized prefusion …

Respiratory syncytial virus infection in adults

HH Nam, MG Ison - bmj, 2019 - bmj.com
Human respiratory syncytial virus (RSV) belongs to the recently defined Pneumoviridae
family, Orthopneumovirus genus. It is a negative sense, single stranded RNA virus that …

Advances in respiratory virus therapeutics–A meeting report from the 6th isirv Antiviral Group conference

JH Beigel, HH Nam, PL Adams, A Krafft, WL Ince… - Antiviral research, 2019 - Elsevier
Abstract The International Society for Influenza and other Respiratory Virus Diseases held its
6th Antiviral Group (isirv-AVG) conference in Rockville, Maryland, November 13–15, 2018 …