Inherited and acquired coagulopathy are frequently associated with major bleeding in
severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage …

Introduction 3. Platelets and endothelium are the source of proteins for coagulation and
inflammation 3.1. Endothelial cell adhesion molecules 3.2. Pletelet glycoproteins for cell …

Objective To review the current knowledge on bone health in patients with hemophilia A and
the underlying pathogenetic mechanisms. Data Sources Original research articles, meta …

Knowledge of the structure and dynamics of proteins and protein assemblies is critical both
for understanding the molecular basis of physiological and patho-physiological processes …

The interplay between innate immunity and coagulation after infection or injury, termed
immunothrombosis, is the primary cause of disseminated intravascular coagulation (DIC), a …

Inhibitors of the coagulation factor XIIa (FXIIa) are attractive to detail the roles of this
protease in hemostasis and thrombosis, to suppress artifact due to contact pathway …

Research regarding the intimate relationship between inflammation and coagulation in
fracture hematoma has attracted increasing attention recently. However, the interaction of …

Vitamin K: Past, Present, Future Essential for normal blood coagulation, possible roles in
bone, vascular, and tumor metabolism, and a nutrient critical to the health of the newborn …

Pregnancy, from implantation to parturition, presents unique and profound challenges to a
women's hemostatic system. During pregnancy, potentially catastrophic bleeding can occur …

FIXa is a serine protease enzyme involved in the intrinsic pathway of the coagulation
cascade. The upstream intervention of the coagulation cascade in selectively inhibiting FIXa …